Ultrathin core-sheath fibers for liposome stabilization

doi:10.1016/j.colsurfb.2014.07.042

CORC > 化学研究所 > 中国科学院化学研究所

	Ultrathin core-sheath fibers for liposome stabilization
	Li, Zhuang 1,2; Kang, Hongliang 1; Li, Qinmei 1,2; Che, Ning 1,2; Liu, Zhijing 1,2; Li, Pingping 1,2; Zhang, Chao 1,2; Liu, Ruigang 1; Huang, Yong 1,3
刊名	COLLOIDS AND SURFACES B-BIOINTERFACES
	2014-10-01
卷号	122 页码:630-637
关键词	Liposome Stabilization Coaxial Electrospinning Core-sheath Nanofibers Sodium Hyaluranate Polyvinylpyrrolidone
ISSN号	0927-7765
DOI	10.1016/j.colsurfb.2014.07.042
英文摘要	Ultrathin core sheath fibers with small unilamellar vesicles (SUVs) in the core were prepared by coaxial electrospinning. SUVs/sodium hyaluranate (HA-Na)/water and polyvinylpyrrolidone (PVP)/ethanol solutions were used as core and sheath fluid in electrospinning, respectively. The ultrathin fibers were characterized by scanning and transmission electron microscopy (SEM and TEM) and laser scanning confocal microscopy (LSCM). The SUVs were successfully encapsulated in the core HA-Na matrix of the ultrathin fibers and are in the elliptic shape. The SUVs encapsulated in the core matrix of the ultrathin fibers have an excellent stability. The SUVs embedded in the ultrathin fibers are stable. When the ultrathin fibers were re-dissolved in water after one-month storage at room temperature, the rehydrated SUVs have the similar size and size distribution as the as-prepared SUVs. The liposome-loaded ultrathin fiber mats have the promising applications in wound healing materials. (C) 2014 Elsevier B.V. All rights reserved.
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000343612900079
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/51427]
专题	中国科学院化学研究所
通讯作者	Liu, Ruigang
作者单位	1.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Tech Inst Phys Er Chem, Tech Inst Phys & Chem, Natl Res Ctr Engn Plast, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Li, Zhuang,Kang, Hongliang,Li, Qinmei,et al. Ultrathin core-sheath fibers for liposome stabilization[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2014,122:630-637.
APA	Li, Zhuang.,Kang, Hongliang.,Li, Qinmei.,Che, Ning.,Liu, Zhijing.,...&Huang, Yong.(2014).Ultrathin core-sheath fibers for liposome stabilization.COLLOIDS AND SURFACES B-BIOINTERFACES,122,630-637.
MLA	Li, Zhuang,et al."Ultrathin core-sheath fibers for liposome stabilization".COLLOIDS AND SURFACES B-BIOINTERFACES 122(2014):630-637.