Nondestructive Thickness Inspection of Capsule Coating by Terahertz Time-Domain Spectroscopy

doi:10.1109/TTHZ.2018.2867265

	Nondestructive Thickness Inspection of Capsule Coating by Terahertz Time-Domain Spectroscopy
	Chang, Tianying 1,2; Guo, Qijia 2; Liu, Lingyu 1; Cui, Hong-Liang2,3
刊名	IEEE TRANSACTIONS ON TERAHERTZ SCIENCE AND TECHNOLOGY
	2018-11-01
卷号	8 期号:6 页码:688-695
关键词	Capsule coating matched filter (MF) thickness determination terahertz time-domain spectroscopy (THz-TDS)
ISSN号	2156-342X
DOI	10.1109/TTHZ.2018.2867265
通讯作者	Chang, Tianying(tchang@jlu.edu.cn)
英文摘要	Accurate online measurement of capsule coating's thickness is desirable because coating is one of the key factors to control the release of active pharmaceutical ingredients. Terahertz time-domain spectroscopy offers a novel and potentially useful technique to examine coatings in terms of its thickness and uniformity quickly and nondestructively. However, online measurement usually requires the simultaneous determination of the upper and bottom parts of the cylindrical shell, in either the reflectio or transmission mode. There is no method for accurate thickness determination in this two-layer structure of capsule coating simultaneously. Improved matched Me is introduced to obtain each layer's thickness for capsule coating with high resolution and accuracy by the terahertz time-domain spectroscopy, without adjusting the fecal point. This method can determine the thicknesses of both the upper and under layers of the capsule coating with high accuracy in a single measurement, whereas traditional method based on time delays cannot identify the thickness due to the low signal-to-noise ratio from the under layer.
资助项目	National Natural Science Foundation of China[61705120] ; Ministry of Science and Technology of China[2015CB755401] ; Department of Science & Technology of Shandong Province[2017GGX10108] ; Department of Science & Technology of Shandong Province[2017GGX10124] ; Youth Science Funds of Shandong Academy of Sciences[2017QN0015] ; Innovation Program of Shandong Academy of Sciences
WOS研究方向	Engineering ; Optics ; Physics
语种	英语
出版者	IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
WOS记录号	WOS:000453572200017
内容类型	期刊论文
源URL	[http://119.78.100.138/handle/2HOD01W0/7163]
专题	中国科学院重庆绿色智能技术研究院
通讯作者	Chang, Tianying
作者单位	1.Qilu Univ Technol, Inst Automat, Shandong Acad Sci, Jinan 250014, Shandong, Peoples R China 2.Jilin Univ, Coll Instrumentat & Elect Engn, Changchun 130061, Jilin, Peoples R China 3.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China
推荐引用方式 GB/T 7714	Chang, Tianying,Guo, Qijia,Liu, Lingyu,et al. Nondestructive Thickness Inspection of Capsule Coating by Terahertz Time-Domain Spectroscopy[J]. IEEE TRANSACTIONS ON TERAHERTZ SCIENCE AND TECHNOLOGY,2018,8(6):688-695.
APA	Chang, Tianying,Guo, Qijia,Liu, Lingyu,&Cui, Hong-Liang.(2018).Nondestructive Thickness Inspection of Capsule Coating by Terahertz Time-Domain Spectroscopy.IEEE TRANSACTIONS ON TERAHERTZ SCIENCE AND TECHNOLOGY,8(6),688-695.
MLA	Chang, Tianying,et al."Nondestructive Thickness Inspection of Capsule Coating by Terahertz Time-Domain Spectroscopy".IEEE TRANSACTIONS ON TERAHERTZ SCIENCE AND TECHNOLOGY 8.6(2018):688-695.