Degradation of triclosan by chlorine dioxide: Reaction mechanism,2,4-dichlorophenol accumulation and toxicity evaluation

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 中国科学院饮用水科学与技术重点实验室

	Degradation of triclosan by chlorine dioxide: Reaction mechanism,2,4-dichlorophenol accumulation and toxicity evaluation
	Chen, Weizhu; Deng, Jing; Chen, Guoyuan; Li, Guoxin; Ma, Xiaoyan; Li, Qingsong; Yu, Jianwei
刊名	CHEMOSPHERE
	2018-09-01
卷号	207 页码:449-456
关键词	Toxicity Triclosan Chlorine dioxide Degradation intermediates
ISSN号	0045-6535
文献子类	Article
英文摘要	The mechanism and toxicity of TCS degradation by ClO2 was investigated. Intermediate products during the oxidation process were identified by GC/MS and LC/MS. A microtox bioassay and a SOS/umu assay were employed to evaluate the acute toxicity and genotoxicity of the resulting solutions during the chlorination process. The results showed that the reaction between TCS and ClO2 was of second-order overall. The pseudo first-order rate constants (k(obs)) exhibited significant dependence on solution pH and chlorine dioxide concentration, with the apparent second-order rate constant, k(app), being 7.07 x 10(4) M-1 s(-1) in the pH range of 6.80 -7.02. TCS decomposition was accompanied by the accumulation of 2,4-dichlorophenol (2,4-DCP), and the maximum molar yield ratios of 2,4-DCP/TCS were in the range of 31.71 %-35.43%. The major intermediates identified were 2,7/2,8-dichlorodibenzop-dioxin (2.7/2.8-Cl2DD), 2,4-DCP, 2,4,6-trichlorophenol (2,4,6-TCP), tetraclosan and pentaclosan. The proposed mechanism for TCS oxidation involved the cleavage of the ether link in TCS, chlorination of the phenolic ring and ring closure of a single TCS molecule. The transformation and degradation of TCS led to reduction of the acute toxicity and genotoxicity. However, irregular fluctuations in the toxicity changes indicated that the oxidation of TCS was not a simultaneous detoxification process. (C) 2018 Elsevier Ltd. All rights reserved.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/41338]
专题	生态环境研究中心_中国科学院饮用水科学与技术重点实验室
推荐引用方式 GB/T 7714	Chen, Weizhu,Deng, Jing,Chen, Guoyuan,et al. Degradation of triclosan by chlorine dioxide: Reaction mechanism,2,4-dichlorophenol accumulation and toxicity evaluation[J]. CHEMOSPHERE,2018,207:449-456.
APA	Chen, Weizhu.,Deng, Jing.,Chen, Guoyuan.,Li, Guoxin.,Ma, Xiaoyan.,...&Yu, Jianwei.(2018).Degradation of triclosan by chlorine dioxide: Reaction mechanism,2,4-dichlorophenol accumulation and toxicity evaluation.CHEMOSPHERE,207,449-456.
MLA	Chen, Weizhu,et al."Degradation of triclosan by chlorine dioxide: Reaction mechanism,2,4-dichlorophenol accumulation and toxicity evaluation".CHEMOSPHERE 207(2018):449-456.