Regio- and Diastereoselective Access to Fused Isoxazolidines via Ru(II)-Catalyzed C-H Activation of Nitrones and Coupling with Perfluoroalkylolefins

doi:10.1021/acs.orglett.7b03775

	Regio- and Diastereoselective Access to Fused Isoxazolidines via Ru(II)-Catalyzed C-H Activation of Nitrones and Coupling with Perfluoroalkylolefins
	Li, Yunyun 1,2; Xie, Fang 1; Liu, Yuan 1; Yang, Xifa 1,2; Li, Xingwei 1
刊名	ORGANIC LETTERS
	2018-01-19
卷号	20 期号:2 页码:437-440
ISSN号	1523-7060
DOI	10.1021/acs.orglett.7b03775
文献子类	Article
英文摘要	The synthsis of fluorinated isoxazolidines in bicyclic settings has been realized via Ru(II)-catalyzed C-H activation of aryl nitrones with perfluoroalkyl-substituted olefins as the coupling partner. The reaction proceeded via initial chelation-assisted C(aryl)-H allylation followed by regio- and diastereoselective intramolecular dipolar addition between the nitrone directing group and the olefin unit.
WOS关键词	1,3-DIPOLAR CYCLOADDITION REACTIONS ; ENANTIOSELECTIVE FLUORINATION ; AZOMETHINE YLIDES ; ORGANIC-SYNTHESIS ; ROOM-TEMPERATURE ; DIRECTING GROUPS ; ZETEKITOXIN-AB ; FUNCTIONALIZATION ; FLUOROALKENYLATION ; PALLADIUM
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000423252400031
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/168610]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者	Li, Xingwei
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Li, Yunyun,Xie, Fang,Liu, Yuan,et al. Regio- and Diastereoselective Access to Fused Isoxazolidines via Ru(II)-Catalyzed C-H Activation of Nitrones and Coupling with Perfluoroalkylolefins[J]. ORGANIC LETTERS,2018,20(2):437-440.
APA	Li, Yunyun,Xie, Fang,Liu, Yuan,Yang, Xifa,&Li, Xingwei.(2018).Regio- and Diastereoselective Access to Fused Isoxazolidines via Ru(II)-Catalyzed C-H Activation of Nitrones and Coupling with Perfluoroalkylolefins.ORGANIC LETTERS,20(2),437-440.
MLA	Li, Yunyun,et al."Regio- and Diastereoselective Access to Fused Isoxazolidines via Ru(II)-Catalyzed C-H Activation of Nitrones and Coupling with Perfluoroalkylolefins".ORGANIC LETTERS 20.2(2018):437-440.