Nontargeted screening of chemical contaminants and illegal additives in food based on liquid chromatography-high resolution mass spectrometry

doi:10.1016/j.trac.2017.07.014

	Nontargeted screening of chemical contaminants and illegal additives in food based on liquid chromatography-high resolution mass spectrometry
	Fu, Yanqing 1,2; Zhao, Chunxia 1,2; Lu, Xin 1,2; Xu, Guowang 1,2
刊名	TRAC-TRENDS IN ANALYTICAL CHEMISTRY
	2017-11-01
卷号	96 页码:89-98
关键词	Nontargeted Screening Liquid Chromatography-mass Spectrometry Food Safety Illegal Additives Chemical Contaminants
ISSN号	0165-9936
DOI	10.1016/j.trac.2017.07.014
文献子类	Article
英文摘要	Nowadays food safety has become one of the focus topics all over the world. Illegal addition of additives and chemical contaminants are the prominent problems. Because of the advantages of high resolution mass spectrometry (HRMS), the combination of liquid chromatography (LC) with HRMS has been more and more used in food safety analysis, but most of related analytical methods have been developed to detect the specific known compounds. For unknown harmful compounds in food, nontargeted screening method is a complementary one. However, there are still a lot of challenges in the nontargeted analysis. Here, the recent studies about sample preparation, LC-HRMS profiling analysis, data pretreatment, differential analysis, identification of unknown compounds in nontargeted screening of chemical contaminants and illegal additives in food are reviewed based on the papers published mainly in 2010-2017, which can be helpful for defining potential risk compounds in food analysis in the future. (C) 2017 Elsevier B.V. All rights reserved.
WOS关键词	TIME-OF-FLIGHT ; VETERINARY DRUG RESIDUES ; PESTICIDE-RESIDUES ; ACCURATE-MASS ; LC-MS ; METABOLOMICS APPROACH ; MULTIRESIDUE METHOD ; CHICKEN MUSCLE ; QTOF-MS ; METABOLITE IDENTIFICATION
WOS研究方向	Chemistry
语种	英语
出版者	ELSEVIER SCI LTD
WOS记录号	WOS:000415910300010
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/168334]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者	Zhao, Chunxia; Xu, Guowang
作者单位	1.Dalian Inst Chem Phys, Chinese Acad Sci, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Fu, Yanqing,Zhao, Chunxia,Lu, Xin,et al. Nontargeted screening of chemical contaminants and illegal additives in food based on liquid chromatography-high resolution mass spectrometry[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY,2017,96:89-98.
APA	Fu, Yanqing,Zhao, Chunxia,Lu, Xin,&Xu, Guowang.(2017).Nontargeted screening of chemical contaminants and illegal additives in food based on liquid chromatography-high resolution mass spectrometry.TRAC-TRENDS IN ANALYTICAL CHEMISTRY,96,89-98.
MLA	Fu, Yanqing,et al."Nontargeted screening of chemical contaminants and illegal additives in food based on liquid chromatography-high resolution mass spectrometry".TRAC-TRENDS IN ANALYTICAL CHEMISTRY 96(2017):89-98.