Fluorometric determination of dopamine by using molybdenum disulfide quantum dots

	Fluorometric determination of dopamine by using molybdenum disulfide quantum dots
	Liu, Xinnan ; Zhang, Wentao ; Huang, Lunjie ; Hu, Na ; Liu, Wei ; Liu, Yingnan ; Li, Sihang ; Yang, Chengyuan ; Suo, Yourui ; Wang, Jianlong
刊名	MICROCHIMICA ACTA
	2018-04-01
英文摘要	A method is described for the rapid fluorometric determination of dopamine (DA) by using molybdenum disulfide quantum dots (MoS2 QDs) that were fabricated via an ammonium hydroxide etching method. The probe has a fluorescence (with excitation/ emission peaks at 267/380 nm) that is quenched by DA with high selectivity over various interferences. This is attributed to a reaction that occurs between DA and the molybdate ions in pH 9 solutions of MoS2 QDs. The formation of organic molybdate complexes and of dopamine-quinone results in strong quenching of the fluorescence of the QDs which is due to both electron transfer and an inner filter effect. Under the optimum conditions, the assay works in the 0.1-100 mu M DA concentration range, with two linear ranges and a 10 nM detection limit. The method was applied to the determination of DA in spiked artificial urine samples, where it gave recoveries ranging from 97.6 to 102.2%, demonstrating that the method a promising tool for rapid and selective detection of DA.
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/13349]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Liu, Xinnan,Zhang, Wentao,Huang, Lunjie,et al. Fluorometric determination of dopamine by using molybdenum disulfide quantum dots[J]. MICROCHIMICA ACTA,2018.
APA	Liu, Xinnan.,Zhang, Wentao.,Huang, Lunjie.,Hu, Na.,Liu, Wei.,...&Wang, Jianlong.(2018).Fluorometric determination of dopamine by using molybdenum disulfide quantum dots.MICROCHIMICA ACTA.
MLA	Liu, Xinnan,et al."Fluorometric determination of dopamine by using molybdenum disulfide quantum dots".MICROCHIMICA ACTA (2018).