Obtaining alantolactone and isoalantolactone from Inula racemose Hook.f. by optimized supercritical fluid extraction

	Obtaining alantolactone and isoalantolactone from Inula racemose Hook.f. by optimized supercritical fluid extraction
	Chi, Xiao-Feng ; Yue, Hui-Lan ; Zhao, Xiao-Hui ; Hu, Feng-Zu
刊名	INDUSTRIAL CROPS AND PRODUCTS
	2016
英文摘要	Inula racemose Hook.f. (I. racemosa) is a traditional herbal medicine with strong anti-fungal and anti-inflammation activity while alantolactone (AL) and isoalantolactone (IAL) are the major active compounds of this plant. The aim of this paper was obtaining AL and IAL from the radix off. racemosa by supercritical fluid extraction (SFE) which was optimized by response surface methodology (RSM). Our results showed that, the optimal conditions for maximum extraction efficiency were as follows: pressure 20 MPa, extraction temperature 50 degrees C, carbon dioxide (CO2) flow rate of 17.0 x 10(-5) kg/s and extraction time of 40 min. Subsequently, an efficient freezing method was developed for purification of AL and IAL in the crude extract obtained from SFE. After purification by freezing, the total content of the target compounds was greatly improved by 30.7%. The results demonstrate that SFE coupled with freezing would be a powerful technique for extraction and purification of AL and IAL from the radix off. racemosa. (C) 2015 Elsevier B.V. All rights reserved.
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/6501]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Chi, Xiao-Feng,Yue, Hui-Lan,Zhao, Xiao-Hui,et al. Obtaining alantolactone and isoalantolactone from Inula racemose Hook.f. by optimized supercritical fluid extraction[J]. INDUSTRIAL CROPS AND PRODUCTS,2016.
APA	Chi, Xiao-Feng,Yue, Hui-Lan,Zhao, Xiao-Hui,&Hu, Feng-Zu.(2016).Obtaining alantolactone and isoalantolactone from Inula racemose Hook.f. by optimized supercritical fluid extraction.INDUSTRIAL CROPS AND PRODUCTS.
MLA	Chi, Xiao-Feng,et al."Obtaining alantolactone and isoalantolactone from Inula racemose Hook.f. by optimized supercritical fluid extraction".INDUSTRIAL CROPS AND PRODUCTS (2016).