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Synthesis of novel biodegradable poly(ethylene glycol) analogue: water-soluble aliphatic polyester with pendant oligo(ethylene glycol) chains
Feng, Lei1,3; Hao, Jian Yuan1,2; Xiong, Cheng Dong1; Deng, Xian Mo1
刊名Chinese chemical letters
2009-12-01
卷号20期号:12页码:1502-1505
关键词Water-soluble Peg analogue 2-((2-(2-methoxyethoxy)ethoxy)methyl)oxirane Ring-opening alternating copolymerization Polyester
ISSN号1001-8417
DOI10.1016/j.cclet.2009.06.013
通讯作者Hao, jian yuan(jyhao@uestc.edu.cn)
英文摘要A novel poly(ethylene glycol) (peg) analogue composed of aliphatic polyester backbone and pendant oligo(ethylene glycol) short chains is reported. the peg analogue is a copolymer synthesized by ring-opening alternating copolymerization of succinic anhydride with 2-((2-(2-metho xyethoxy)ethoxy)methyl)oxirane. the structure of the copolymer was confirmed by (1)h nmr spectrum. the effects of the monomer feed ratio on the copolymerization were studied and the polymerization mechanism was given. the peg analogue disclosed is water-soluble and expected to have promising applications in biomedical fields as a substitute of peg due to the existence of degradable ester bond in the backbone. (c) 2009 jian yuan hao. published by elsevier b.v. on behalf of chinese chemical society. all rights reserved.
WOS研究方向Chemistry
WOS类目Chemistry, Multidisciplinary
语种英语
出版者ELSEVIER SCIENCE INC
WOS记录号WOS:000273015800029
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2395802
专题中国科学院大学
通讯作者Hao, Jian Yuan
作者单位1.Chinese Acad Sci, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China
2.Univ Elect Sci & Technol China, Sch Microeletron & Solid State Elect, Chengdu 610054, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714
Feng, Lei,Hao, Jian Yuan,Xiong, Cheng Dong,et al. Synthesis of novel biodegradable poly(ethylene glycol) analogue: water-soluble aliphatic polyester with pendant oligo(ethylene glycol) chains[J]. Chinese chemical letters,2009,20(12):1502-1505.
APA Feng, Lei,Hao, Jian Yuan,Xiong, Cheng Dong,&Deng, Xian Mo.(2009).Synthesis of novel biodegradable poly(ethylene glycol) analogue: water-soluble aliphatic polyester with pendant oligo(ethylene glycol) chains.Chinese chemical letters,20(12),1502-1505.
MLA Feng, Lei,et al."Synthesis of novel biodegradable poly(ethylene glycol) analogue: water-soluble aliphatic polyester with pendant oligo(ethylene glycol) chains".Chinese chemical letters 20.12(2009):1502-1505.
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