QQ客服 官方微博 反馈留言

	Electrochemical detection of methimazole by capillary electrophoresis at a carbon fiber microdisk electrode
	Sun, JY; Zheng, CY; Xiao, XL; Niu, L; You, TY; Wang, EK
刊名	Electroanalysis
	2005-09-01
卷号	17期号:18页码:1675-1680
关键词	Electrochemical detection Capillary electrophoresis Carbon fiber microdisk electrode Methimazole
ISSN号	1040-0397
DOI	10.1002/elan.200403272
通讯作者	You, ty()
英文摘要	We developed a sensitive, simple and low cost method to determine methimazole based on capillary electrophoresis with electrochemical detection (ce-ec) at a carbon fiber microdisk electrode (cfe). we investigated the effects of detection potential, the concentration and ph value of the phosphate buffer, and injection time as well as separation voltage on the detection of methimazole. under the optimized conditions: the detection potential at 1.30 v, 10 mmol/l phosphate buffer (ph 7.0), injection time 30 s at a height of 20 centimeter and separation voltage at 15 kv, the linear range was obtained from 1.0 x 10(-7) to 2.0 x 10(-4) mol/l, covering 3 orders of magnitude with a correlation coefficient of 0.9995. the lod (s/n 3) obtained was 5.0 x 10(-8) mol/l. the rsd of migration time and peak current for 2.0 x 10(-4) mol/l methimazole was 1.04% and 1.54% (n = 10), respectively. the method was also used to analyze methimazole tablets and human urine sample.
WOS关键词	SIMPLIFIED AMPEROMETRIC DETECTION ; DOPED DIAMOND ELECTRODE ; FLOW-INJECTION ; CARBIMAZOLE ; SEPARATION ; CHIPS ; IMMUNOASSAYS ; GLUCOSE
WOS研究方向	Chemistry ; Electrochemistry
WOS类目	Chemistry, Analytical ; Electrochemistry
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000232407100010
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2377538
专题	中国科学院大学
通讯作者	You, TY
作者单位	1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Changchun 130022, Peoples R China 3.Heilongjiang Univ, Life Sci Coll, Harbin 150080, Peoples R China
推荐引用方式 GB/T 7714	Sun, JY,Zheng, CY,Xiao, XL,et al. Electrochemical detection of methimazole by capillary electrophoresis at a carbon fiber microdisk electrode[J]. Electroanalysis,2005,17(18):1675-1680.
APA	Sun, JY,Zheng, CY,Xiao, XL,Niu, L,You, TY,&Wang, EK.(2005).Electrochemical detection of methimazole by capillary electrophoresis at a carbon fiber microdisk electrode.Electroanalysis,17(18),1675-1680.
MLA	Sun, JY,et al."Electrochemical detection of methimazole by capillary electrophoresis at a carbon fiber microdisk electrode".Electroanalysis 17.18(2005):1675-1680.

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。