| Growth inhibition and altered gene transcript levels in earthworms (eisenia fetida) exposed to 2,2',4,4'-tetrabromodiphenyl ether | |
| Xu, Xiang-bo1,2,3; Shi, Ya-juan1; Lu, Yong-long1; Zheng, Xiao-qi1,2,4; Ritchie, R. J.5 | |
| 刊名 | Archives of environmental contamination and toxicology
 |
| 2015-07-01 | |
| 卷号 | 69期号:1页码:1-7 |
| ISSN号 | 0090-4341 |
| DOI | 10.1007/s00244-014-0125-4 |
| 通讯作者 | Shi, ya-juan(yajuanshi@rcees.ac.cn) |
| 英文摘要 | The toxic effects of the ubiquitous pollutant 2,2',4,4'-tetrabromodiphenyl ether (bde-47) on the earthworm eisenia fetida were assessed by determining growth-inhibition and gene transcript levels of superoxide dismutase (sod), catalase (cat), glutathione transferase (gst), and transcriptional changes of the stress-response gene (heat-shock protein 70 [hsp70]). somatic growth and growth-inhibition rates in all bde-47-treated groups were significantly different from those of the controls. the sod gene transcripts were upregulated at all exposure doses and reached the maximum at the concentration of 400 mg/kg dry weight (dw) (3.84-fold, p < 0.01), which protected earthworms from oxidative stresses. however, downregulation of cat and hsp70 was present in all exposure doses and reached to the minimum at concentrations of 400 mg/kg dw (0.07-fold, p < 0.01 and 0.06-fold, p < 0.01, respectively). upregulation of gst gene transcript level presented significant changes at concentrations of 10 (2.69-fold, p < 0.05) and 100 mg/kg dw (2.55-fold, p < 0.05). sod maintained a dynamic balance to upregulate sod expression to eliminate superoxide radicals in all dosage treatments, but downregulation of cat decreased the ability to eliminate hydrogen peroxide. these changes could result in biochemical and physiological disturbances in earthworms. |
| WOS关键词 | POLYBROMINATED DIPHENYL ETHERS ; CADMIUM EXPOSURE ; ARTIFICIAL SOIL ; BREAST-MILK ; EXPRESSION ; RESPONSES ; METALLOTHIONEIN ; CLONING ; PBDES ; CELOMOCYTES |
| WOS研究方向 | Environmental Sciences & Ecology ; Toxicology |
| WOS类目 | Environmental Sciences ; Toxicology |
| 语种 | 英语 |
| 出版者 | SPRINGER |
| WOS记录号 | WOS:000355685600001 |
| 内容类型 | 期刊论文 |
| URI标识 | http://www.corc.org.cn/handle/1471x/2376672 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Shi, Ya-juan |
| 作者单位 | 1.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Urban & Reg Ecol, Beijing 100085, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Beijing Municipal Environm Monitoring Ctr, Beijing 100048, Peoples R China 4.Natl Ctr Climate Change Strategy & Int Cooperat, Beijing 100038, Peoples R China 5.Prince Songkla Univ Phuket, Fac Technol & Environm, Trop Environm Plant Biol Unit, Phuket 83120, Thailand |
| 推荐引用方式 GB/T 7714 | Xu, Xiang-bo,Shi, Ya-juan,Lu, Yong-long,et al. Growth inhibition and altered gene transcript levels in earthworms (eisenia fetida) exposed to 2,2',4,4'-tetrabromodiphenyl ether[J]. Archives of environmental contamination and toxicology,2015,69(1):1-7. |
| APA | Xu, Xiang-bo,Shi, Ya-juan,Lu, Yong-long,Zheng, Xiao-qi,&Ritchie, R. J..(2015).Growth inhibition and altered gene transcript levels in earthworms (eisenia fetida) exposed to 2,2',4,4'-tetrabromodiphenyl ether.Archives of environmental contamination and toxicology,69(1),1-7. |
| MLA | Xu, Xiang-bo,et al."Growth inhibition and altered gene transcript levels in earthworms (eisenia fetida) exposed to 2,2',4,4'-tetrabromodiphenyl ether".Archives of environmental contamination and toxicology 69.1(2015):1-7. |
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