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Dmap-catalyzed diels-alder reaction of 3-hydroxy-2-pyrone and methyleneindolinones for the synthesis of spirocyclic oxindolesl
Zhou, Ming-Qiang1,2; Zhao, Jian-Qiang1,2; You, Yong1,2; Xu, Xiao-Ying1; Zhang, Xiao-Mei1; Yuan, Wei-Cheng1
刊名Tetrahedron
2015-06-10
卷号71期号:23页码:3903-3908
关键词Diels-alder reaction 3-hydroxy-2-pyrone Methyleneindolinones Spirocyclic oxindoles 4-dimethylaminopyridine
ISSN号0040-4020
DOI10.1016/j.tet.2015.04.032
通讯作者Yuan, wei-cheng(yuanwc@cioc.ac.cn)
英文摘要An efficient diels-alder reaction of 3-hydroxy-2-pyrone with a wide range of methyleneindolinones has been developed by employing 4-dimethylaminopyridine as a catalyst under mild reaction conditions. this process provides a promising method for the construction of structurally diverse spirocyclic oxindoles containing bicyclic lactone motif with moderate diastereoselectivities and good to excellent yields. (c) 2015 elsevier ltd. all rights reserved.
WOS关键词ASYMMETRIC-SYNTHESIS ; HIGHLY EFFICIENT ; STEREOSELECTIVE CONSTRUCTION ; 3-ISOTHIOCYANATO OXINDOLES ; NATURAL-PRODUCTS ; SPIRO COMPOUNDS ; SPIROOXINDOLES ; MICHAEL ; STEREOCENTERS ; 2-PYRONES
WOS研究方向Chemistry
WOS类目Chemistry, Organic
语种英语
出版者PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号WOS:000356125500018
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2376450
专题中国科学院大学
通讯作者Yuan, Wei-Cheng
作者单位1.Chinese Acad Sci, Chengdu Inst Organ Chem, Natl Engn Res Ctr Chiral Drugs, Chengdu 610041, Peoples R China
2.Univ Chinese Acad Sci, Being 100049, Peoples R China
推荐引用方式
GB/T 7714
Zhou, Ming-Qiang,Zhao, Jian-Qiang,You, Yong,et al. Dmap-catalyzed diels-alder reaction of 3-hydroxy-2-pyrone and methyleneindolinones for the synthesis of spirocyclic oxindolesl[J]. Tetrahedron,2015,71(23):3903-3908.
APA Zhou, Ming-Qiang,Zhao, Jian-Qiang,You, Yong,Xu, Xiao-Ying,Zhang, Xiao-Mei,&Yuan, Wei-Cheng.(2015).Dmap-catalyzed diels-alder reaction of 3-hydroxy-2-pyrone and methyleneindolinones for the synthesis of spirocyclic oxindolesl.Tetrahedron,71(23),3903-3908.
MLA Zhou, Ming-Qiang,et al."Dmap-catalyzed diels-alder reaction of 3-hydroxy-2-pyrone and methyleneindolinones for the synthesis of spirocyclic oxindolesl".Tetrahedron 71.23(2015):3903-3908.
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