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	Traceable nanoparticle delivery of small interfering rna and retinoic acid with temporally release ability to control neural stem cell differentiation for alzheimer's disease therapy
	Zhang, Ran1,2; Li, Yan1; Hu, Bingbing1; Lu, Zhiguo1,3; Zhang, Jinchao2; Zhang, Xin1
刊名	Advanced materials
	2016-08-10
卷号	28期号:30页码:6345-+
ISSN号	0935-9648
DOI	10.1002/adma.201600554
通讯作者	Zhang, jinchao(jczhang6970@163.com)
英文摘要	Nanoparticles that can efficiently control the differentiation of neural stem cells (nscs) into neurons are developed for alzheimer's disease (ad) therapy. the treatment with these nanoparticles results in an attenuation of neuronal loss and rescues memory deficiencies in mice. the system can also be used to monitor the transplantation site, as well as the migration of nscs in real time. therefore, the system is proposed to open up new avenues for ad treatment.
WOS关键词	SIRNA DELIVERY ; IMPROVE COGNITION ; TRANSGENIC MODELS ; SMALL MOLECULES ; DRUG-DELIVERY ; BRAIN ; TRANSPLANTATION ; PROLIFERATION ; DERIVATIVES ; EFFICIENCY
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS类目	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000382480100006
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2375672
专题	中国科学院大学
通讯作者	Zhang, Jinchao
作者单位	1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Hebei Univ, Key Lab Med Chem & Mol Diag, Minist Educ, Coll Chem & Environm Sci,Chem Biol Key Lab Hebei, Baoding 071002, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Ran,Li, Yan,Hu, Bingbing,et al. Traceable nanoparticle delivery of small interfering rna and retinoic acid with temporally release ability to control neural stem cell differentiation for alzheimer's disease therapy[J]. Advanced materials,2016,28(30):6345-+.
APA	Zhang, Ran,Li, Yan,Hu, Bingbing,Lu, Zhiguo,Zhang, Jinchao,&Zhang, Xin.(2016).Traceable nanoparticle delivery of small interfering rna and retinoic acid with temporally release ability to control neural stem cell differentiation for alzheimer's disease therapy.Advanced materials,28(30),6345-+.
MLA	Zhang, Ran,et al."Traceable nanoparticle delivery of small interfering rna and retinoic acid with temporally release ability to control neural stem cell differentiation for alzheimer's disease therapy".Advanced materials 28.30(2016):6345-+.

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