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Epidemiology and phylogenetic analysis of crimean-congo hemorrhagic fever viruses in xinjiang, china
Sun, Surong2; Dai, Xiang3; Aishan, Muhetaer3; Wang, Xinhui3; Meng, Weiwei3; Feng, Conghui3; Zhang, Fuchun2; Hang, Changshou4; Hu, Zhihong1; Zhang, Yujiang3
刊名Journal of clinical microbiology
2009-08-01
卷号47期号:8页码:2536-2543
ISSN号0095-1137
DOI10.1128/jcm.00265-09
通讯作者Hu, zhihong(huzh@wh.iov.cn)
英文摘要In 2004 and 2005, an epidemiological survey of crimean-congo hemorrhagic fever virus (cchfv) was conducted in xinjiang, china. a total of 5,629 serum samples of human and livestock were collected and tested for the cchfv antibody, and 17,319 ticks were collected for viral identification. reverse passive hemagglutination inhibition assays showed that the average prevalence of cchfv antibody was 1.7% for the humans and 12.7% for the livestock. a relatively high antibody prevalence, ranging from 19.1% to 23.4%, was found in the livestock of the northwest, southwest, and northeast parts of the tarim basin. when the ticks were pooled to inoculate suckling mice, followed by reverse transcription-pcr (rt-pcr) to detect cchfv rna, the average rt-pcr-positive rates for hyalomma asiaticum kozlovi and h. asiaticum asiaticum were 12.9% and 2.6%, respectively. a significant correlation was found between the antibody prevalence in the livestock and the cchfv prevalence in h. asiaticum of the same geographic region. no cchfv rna was detected in dermacentor nivenus, rhipicephalus turanius, or rhipicephalus sanguineus. a total of 27 partial s segments of cchfvs were sequenced and used for phylogeny analysis. all but one chinese isolate grouped into the asia 1 clade, which contains the strains from xinjiang and uzbekistan, while the other strain, fub90009, grouped with strains from the middle east.
WOS关键词M-RNA SEGMENT ; OUTBREAK ; AFRICA ; DIVERSITY ; RUSSIA ; EUROPE ; ASIA
WOS研究方向Microbiology
WOS类目Microbiology
语种英语
出版者AMER SOC MICROBIOLOGY
WOS记录号WOS:000268499600027
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2375566
专题武汉病毒研究所
通讯作者Hu, Zhihong
作者单位1.Chinese Acad Sci, State Key Lab Virol, Wuhan Inst Virol, Wuhan 430071, Peoples R China
2.Xinjiang Univ, Coll Life Sci & Technol, Xinjiang Key Lab Biol Resources & Genet Engn, Urumqi, Peoples R China
3.Ctr Dis Control & Prevent Xinjiang Uygur Autonomo, Urumqi, Peoples R China
4.Chinese Ctr Dis Control & Prevent, Inst Virol, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Sun, Surong,Dai, Xiang,Aishan, Muhetaer,et al. Epidemiology and phylogenetic analysis of crimean-congo hemorrhagic fever viruses in xinjiang, china[J]. Journal of clinical microbiology,2009,47(8):2536-2543.
APA Sun, Surong.,Dai, Xiang.,Aishan, Muhetaer.,Wang, Xinhui.,Meng, Weiwei.,...&Zhang, Yujiang.(2009).Epidemiology and phylogenetic analysis of crimean-congo hemorrhagic fever viruses in xinjiang, china.Journal of clinical microbiology,47(8),2536-2543.
MLA Sun, Surong,et al."Epidemiology and phylogenetic analysis of crimean-congo hemorrhagic fever viruses in xinjiang, china".Journal of clinical microbiology 47.8(2009):2536-2543.
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