| A conserved structural motif shared by eiav gp90 and hiv gp120 | |
| Li, HG; Tong, X; Shen, T; Shen, RX; Zhang, XY; Shao, YM | |
| 刊名 | Chinese science bulletin
 |
| 2005-10-01 | |
| 卷号 | 50期号:20页码:2393-2394 |
| 关键词 | Eiav Hiv N-glycosylation Epitope Gp120 Gp90 |
| ISSN号 | 1001-6538 |
| DOI | 10.1360/982005-979 |
| 通讯作者 | Zhang, xy() |
| 英文摘要 | Both hiv and eiav belong to the retroviridae family and lentivirus genus. they share considerable similarity at gene structural and component level. hotzel proposed that two variable regions and surrounding amino acids of eiav gp90 might adopt the same topology as v1, v2 and bridging sheet of hiv gp120. these regions map to v3, v4 and surrounding amino acids of eiav gp90. based on this proposal, we further analyzed the distribution profile of n-glycosylation site and linear epitope for eiav gp90 and hiv gp120 at these regions. our results demonstrated that eiav gp90 and hiv gp120 are highly similar at these two aspects. most likely, v3, v4 and surrounding amino acids of eiav gp90 adopt the same topology structure as v1, v2 and bridging sheet of hiv gp120. |
| WOS关键词 | INFECTIOUS-ANEMIA VIRUS ; ENVELOPE GLYCOPROTEIN ; TYPE-1 GP120 |
| WOS研究方向 | Science & Technology - Other Topics |
| WOS类目 | Multidisciplinary Sciences |
| 语种 | 英语 |
| 出版者 | SCIENCE PRESS |
| WOS记录号 | WOS:000234331800024 |
| 内容类型 | 期刊论文 |
| URI标识 | http://www.corc.org.cn/handle/1471x/2375241 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Zhang, XY |
| 作者单位 | 1.CDC, Dept Res Virol & Immunol, Natl Ctr AIDS STD Control & Prevent, Beijing 100052, Peoples R China 2.Chinese Acad Sci, Wuhan Inst Virol, Wuhan 430071, Peoples R China 3.Harbin Vet Res Inst, Dept Res EIAV, Harbin 150001, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, HG,Tong, X,Shen, T,et al. A conserved structural motif shared by eiav gp90 and hiv gp120[J]. Chinese science bulletin,2005,50(20):2393-2394. |
| APA | Li, HG,Tong, X,Shen, T,Shen, RX,Zhang, XY,&Shao, YM.(2005).A conserved structural motif shared by eiav gp90 and hiv gp120.Chinese science bulletin,50(20),2393-2394. |
| MLA | Li, HG,et al."A conserved structural motif shared by eiav gp90 and hiv gp120".Chinese science bulletin 50.20(2005):2393-2394. |
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