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	Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation
	Lei, Jie1,2,3; Xu, Zhi-Gang3; Li, Shi-Qiang3; Xu, Jia3; Zhu, Jin2,3; Chen, Zhong-Zhu3
刊名	Molecular diversity
	2016-11-01
卷号	20期号:4页码:859-865
关键词	Cyclization Heterocycles Ugi-type multicomponent reactions Udc strategy Intramolecular amidation One-pot procedure Mcrs
ISSN号	1381-1991
DOI	10.1007/s11030-016-9679-6
通讯作者	Xu, zhi-gang(xuzhigangyours@yahoo.com) ; Chen, zhong-zhu(18883138277@163.com)
英文摘要	Four series of heterocyclic compounds were obtained using ugi-type multicomponent reactions (mcrs) with methyl 2-formylbenzoate as one of the starting materials. a facile and efficient one-pot procedure was suitable for all the mcrs under acidic conditions. this process provided access to four series of complex and potentially biologically active scaffolds.
WOS关键词	MOLECULAR DIVERSITY ; DRUG DISCOVERY ; ONE-POT ; ISOCYANIDES ; CHEMISTRY ; STRATEGY ; BENZIMIDAZOLES ; CONDENSATION ; CHEMOTYPES ; TETRAZOLES
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy
WOS类目	Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Medicinal ; Chemistry, Multidisciplinary
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000385192900007
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2374822
专题	中国科学院大学
通讯作者	Xu, Zhi-Gang; Chen, Zhong-Zhu
作者单位	1.Chinese Acad Sci, Chengdu Inst Organ Chem, Key Lab Asymmetr Synth & Chiral Technol Sichuan P, Chengdu 610041, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chongqing Univ Arts & Sci, Chongqing Engn Lab Targeted & Innovat Therapeut, Chongqing Key Lab Kinase Modulators Innovat Med, IATTI, 319 Honghe Ave, Chongqing 402160, Peoples R China
推荐引用方式 GB/T 7714	Lei, Jie,Xu, Zhi-Gang,Li, Shi-Qiang,et al. Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation[J]. Molecular diversity,2016,20(4):859-865.
APA	Lei, Jie,Xu, Zhi-Gang,Li, Shi-Qiang,Xu, Jia,Zhu, Jin,&Chen, Zhong-Zhu.(2016).Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation.Molecular diversity,20(4),859-865.
MLA	Lei, Jie,et al."Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation".Molecular diversity 20.4(2016):859-865.

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