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	A new strain of crimean-congo hemorrhagic fever virus isolated from xinjiang, china
	Guo, Rong1; Shen, Shu2; Zhang, Yanfang2; Shi, Junming2; Su, Zhengyuan2; Liu, Dan3; Liu, Jinliang2; Yang, Juan2; Wang, Qiguo1; Hu, Zhihong1
刊名	Virologica sinica
	2017-02-01
卷号	32期号:1页码:80-88
关键词	Crimean-congo hemorrhagic fever virus (cchfv) Newborn mice Genotype Phylogenetic analysis
ISSN号	1674-0769
DOI	10.1007/s12250-016-3936-9
通讯作者	Zhang, yujiang(xjsyzhang@163.com) ; Deng, fei(df@wh.iov.cn)
英文摘要	Crimean-congo hemorrhagic fever virus (cchfv) is a highly pathogenic tick-borne virus with a fatality rate of up to 50% in humans. cchfv is widely distributed in countries around the world. outbreaks of cchfv infection in humans have occurred in prior years in xinjiang province, china. epidemiological surveys have detected cchfv rna in ticks and animals; however, few isolates were identified. in this study, we identified and isolated a new cchfv strain from hyalomma asiaticum asiaticum ticks collected from north of tarim basin in xinjiang, china. a preliminary investigation of infection and antigens expression of cchfv was performed in newborn mice. the target tissues for cchfv replication in newborn mice were identified. the analysis of the phylogenetic relationships with other chinese strains suggested that diverse genotypes of cchfv have circulated in xinjiang for years. these findings provide important insights into our understanding of cchfv infection and evolution as well as disease prevention and control for local residents.
WOS关键词	REASSORTMENT ; EVOLUTION
WOS研究方向	Virology
WOS类目	Virology
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000396155400010
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2373451
专题	武汉病毒研究所
通讯作者	Zhang, Yujiang; Deng, Fei
作者单位	1.Ctr Dis Control & Prevent Xinjiang Uygur Autonomo, Urumqi 830002, Xinjiang, Peoples R China 2.Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China 3.Wuhan Univ Sci & Technol, Sch Med, Wuhan 430065, Peoples R China
推荐引用方式 GB/T 7714	Guo, Rong,Shen, Shu,Zhang, Yanfang,et al. A new strain of crimean-congo hemorrhagic fever virus isolated from xinjiang, china[J]. Virologica sinica,2017,32(1):80-88.
APA	Guo, Rong.,Shen, Shu.,Zhang, Yanfang.,Shi, Junming.,Su, Zhengyuan.,...&Deng, Fei.(2017).A new strain of crimean-congo hemorrhagic fever virus isolated from xinjiang, china.Virologica sinica,32(1),80-88.
MLA	Guo, Rong,et al."A new strain of crimean-congo hemorrhagic fever virus isolated from xinjiang, china".Virologica sinica 32.1(2017):80-88.

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