Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: Analysis by liquid chromatography/electrospray ion trap mass spectrometry

	Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: Analysis by liquid chromatography/electrospray ion trap mass spectrometry
	Zhou, Da-Yong 1; Xing, Rong 2; Xu, Qing 1; Xue, Xing-Ya 1; Zhang, Fei-Fang 1; Liang, Xin-Miao 1
刊名	journal of pharmaceutical and biomedical analysis
	2008-02-13
卷号	46 期号:3 页码:543-549
关键词	LC-MSn polymethoxylated flavones Fructus aurantii rat metabolism
通讯作者	梁鑫淼
产权排序	1;1
英文摘要	a lc with full scan msn method was developed in order to investigate the in vivo absorption and biotransformation of polymethoxylated flavones (pmfs) by analysis of plasma samples from rats after ingestion of fructus aurantii extract. four parent compounds and six metabolites with intact flavonoid structures were tentatively identified. the metabolites were either glucuronides of parent compounds or glucuronides of demethylated products of parent compounds. (c) 2007 elsevier b.v. all rights reserved.
WOS标题词	science & technology ; physical sciences ; life sciences & biomedicine
类目[WOS]	chemistry, analytical ; pharmacology & pharmacy
研究领域[WOS]	chemistry ; pharmacology & pharmacy
关键词[WOS]	cell-lines ; nobiletin ; biotransformation ; identification ; absorption ; hamsters ; urine ; array ; peel
收录类别	SCI
原文出处	true
语种	英语
WOS记录号	WOS:000253100400016
公开日期	2010-11-30
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/100193]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Dalinan Med Univ, Dept Pathol Physiol, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Zhou, Da-Yong,Xing, Rong,Xu, Qing,et al. Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: Analysis by liquid chromatography/electrospray ion trap mass spectrometry[J]. journal of pharmaceutical and biomedical analysis,2008,46(3):543-549.
APA	Zhou, Da-Yong,Xing, Rong,Xu, Qing,Xue, Xing-Ya,Zhang, Fei-Fang,&Liang, Xin-Miao.(2008).Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: Analysis by liquid chromatography/electrospray ion trap mass spectrometry.journal of pharmaceutical and biomedical analysis,46(3),543-549.
MLA	Zhou, Da-Yong,et al."Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: Analysis by liquid chromatography/electrospray ion trap mass spectrometry".journal of pharmaceutical and biomedical analysis 46.3(2008):543-549.