The structure of a sulfated galactan from Porphyra haitanensis and its in vivo antioxidant activity

doi:10.1016/j.carres.2003.09.015

	The structure of a sulfated galactan from Porphyra haitanensis and its in vivo antioxidant activity
	Zhang, QB; Li, N; Liu, XG; Zhao, ZQ; Li, Z; Xu, ZH
刊名	CARBOHYDRATE RESEARCH
	2004-01-02
卷号	339 期号:1 页码:105-+
关键词	Porphyra Haitanensis Sulfated Galactan Chemical Structure Nmr Spectroscopy In Vivo Antioxidant Activity
ISSN号	0008-6215
DOI	10.1016/j.carres.2003.09.015
文献子类	Article
英文摘要	The sulfated galactan fraction F1 isolated from the red seaweed, Porphyra haitanensis, showed typical porphyran structure. It has a linear backbone of alternating 3-linked beta-D-galactosyl units and 4-linked alpha-L-galactosyl 6-sulfate and 3,6-anhydro-alpha-L-galactosyl units. The L-residues are mainly composed of alpha-L-galactosyl 6-sulfate units, and the 3,6-anhydrogalactosyl units are minor. Partial methylation occurred at the C-6 position of the D-galactosyl units and at the C-2 position of the 3,6-anhydro-alpha-L-galactosyl units. Intraperitoneal administration of F1 significantly decreased the lipid peroxidation in aging mice. F1 treatment increased the total antioxidant capacity and the activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in aging mice. The results indicated that F1 had significant in vivo antioxidant activity. (C) 2003 Elsevier Ltd. All rights reserved.; The sulfated galactan fraction F1 isolated from the red seaweed, Porphyra haitanensis, showed typical porphyran structure. It has a linear backbone of alternating 3-linked beta-D-galactosyl units and 4-linked alpha-L-galactosyl 6-sulfate and 3,6-anhydro-alpha-L-galactosyl units. The L-residues are mainly composed of alpha-L-galactosyl 6-sulfate units, and the 3,6-anhydrogalactosyl units are minor. Partial methylation occurred at the C-6 position of the D-galactosyl units and at the C-2 position of the 3,6-anhydro-alpha-L-galactosyl units. Intraperitoneal administration of F1 significantly decreased the lipid peroxidation in aging mice. F1 treatment increased the total antioxidant capacity and the activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in aging mice. The results indicated that F1 had significant in vivo antioxidant activity. (C) 2003 Elsevier Ltd. All rights reserved.
学科主题	Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Organic
URL标识	查看原文
语种	英语
WOS记录号	WOS:000187803900011
公开日期	2010-12-22
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/3581]
专题	海洋研究所_海洋生物技术研发中心
作者单位	Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Zhang, QB,Li, N,Liu, XG,et al. The structure of a sulfated galactan from Porphyra haitanensis and its in vivo antioxidant activity[J]. CARBOHYDRATE RESEARCH,2004,339(1):105-+.
APA	Zhang, QB,Li, N,Liu, XG,Zhao, ZQ,Li, Z,&Xu, ZH.(2004).The structure of a sulfated galactan from Porphyra haitanensis and its in vivo antioxidant activity.CARBOHYDRATE RESEARCH,339(1),105-+.
MLA	Zhang, QB,et al."The structure of a sulfated galactan from Porphyra haitanensis and its in vivo antioxidant activity".CARBOHYDRATE RESEARCH 339.1(2004):105-+.