Preparation and evaluation of rigid porous polyacrylamide-based strong cation-exchange monolithic columns for capillary electrochromatography

	Preparation and evaluation of rigid porous polyacrylamide-based strong cation-exchange monolithic columns for capillary electrochromatography
	Dong, Jing ; Ou, Junjie ; Dong, Xiaoli ; Wu, Renan ; Yel, Mingliang ; Zou, Hanfa
刊名	journal of separation science
	2007-11-01
卷号	30 期号:17 页码:2986-2992
关键词	basic drugs capillary electrochromatography hydrophilic monomers monolith column strong cation-exchange
ISSN号	1615-9306
通讯作者	邹汉法
产权排序	1;1
英文摘要	a cec monolithic column with strong cation-exchange (scx) stationary phase based on hydrophilic monomers was prepared by in situ polymerization of acrylamide, methylenebisacrylamide, and 2-acrylamido-2-methyl-1-propanesulfonic acid (amps) in a complete organic binary porogenic solvent consisting of dmso and dodecanol. the sulfonic groups provided by the monomer amps on the surface of the stationary phase generate an eof from anode to cathode, and serve as an scx stationary phase at the same time. the monolithic stationary phase exhibited normal-phase chromatographic behavior for neutral analytes. for charged analytes, electrostatic interaction/repulsion with the monolith was observed. the strong scx monolithic column has been successfully employed in the electrochromatographic separation of basic drugs, peptides, and alkaloids extracted from natural products.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, analytical
研究领域[WOS]	chemistry
关键词[WOS]	stationary phases ; reversed-phase ; mixed-mode ; separation ; peptides ; chromatography ; retention
收录类别	SCI
原文出处	true
语种	英语
WOS记录号	WOS:000251461500025
公开日期	2010-11-30
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/99357]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China 2.Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China
推荐引用方式 GB/T 7714	Dong, Jing,Ou, Junjie,Dong, Xiaoli,et al. Preparation and evaluation of rigid porous polyacrylamide-based strong cation-exchange monolithic columns for capillary electrochromatography[J]. journal of separation science,2007,30(17):2986-2992.
APA	Dong, Jing,Ou, Junjie,Dong, Xiaoli,Wu, Renan,Yel, Mingliang,&Zou, Hanfa.(2007).Preparation and evaluation of rigid porous polyacrylamide-based strong cation-exchange monolithic columns for capillary electrochromatography.journal of separation science,30(17),2986-2992.
MLA	Dong, Jing,et al."Preparation and evaluation of rigid porous polyacrylamide-based strong cation-exchange monolithic columns for capillary electrochromatography".journal of separation science 30.17(2007):2986-2992.