Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila | |
Wang, Cui-Cui1,2; Liu, Hai-Zhou1; Liu, Ming1; Zhang, Yu-Yan1; Li, Tian-Tian1,2; Lin, Xiu-Kun1 | |
刊名 | MOLECULES |
2011-04-01 | |
卷号 | 16期号:4页码:2796-2801 |
关键词 | Polyketide Chromone Indole Alkaloid Mosher Exophiala Pisciphila |
ISSN号 | 1420-3049 |
DOI | 10.3390/molecules16042796 |
文献子类 | Article |
英文摘要 | A new polyketide compound 1 and a new naturally occurring chromone derivative 2, along with two known indole alkaloids 3-4 were characterized from the ethyl acetate extract of a soil-derived fungal strain, Exophiala pisciphila PHF-9. The structures of compounds 1-4 were established by detailed spectroscopic analysis and comparison with literature data. The absolute configuration of 1 was determined by a modified Mosher's method. Compound 1 exhibited moderate cytotoxicity against A-549, Hela, PANC-28 and BEL-7402 cell lines.; A new polyketide compound 1 and a new naturally occurring chromone derivative 2, along with two known indole alkaloids 3-4 were characterized from the ethyl acetate extract of a soil-derived fungal strain, Exophiala pisciphila PHF-9. The structures of compounds 1-4 were established by detailed spectroscopic analysis and comparison with literature data. The absolute configuration of 1 was determined by a modified Mosher's method. Compound 1 exhibited moderate cytotoxicity against A-549, Hela, PANC-28 and BEL-7402 cell lines. |
学科主题 | Chemistry |
URL标识 | 查看原文 |
语种 | 英语 |
WOS记录号 | WOS:000289236200005 |
公开日期 | 2012-07-03 |
内容类型 | 期刊论文 |
源URL | [http://ir.qdio.ac.cn/handle/337002/11828] |
专题 | 海洋研究所_实验海洋生物学重点实验室 |
作者单位 | 1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Cui-Cui,Liu, Hai-Zhou,Liu, Ming,et al. Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila[J]. MOLECULES,2011,16(4):2796-2801. |
APA | Wang, Cui-Cui,Liu, Hai-Zhou,Liu, Ming,Zhang, Yu-Yan,Li, Tian-Tian,&Lin, Xiu-Kun.(2011).Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila.MOLECULES,16(4),2796-2801. |
MLA | Wang, Cui-Cui,et al."Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila".MOLECULES 16.4(2011):2796-2801. |
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