Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila
Wang, Cui-Cui1,2; Liu, Hai-Zhou1; Liu, Ming1; Zhang, Yu-Yan1; Li, Tian-Tian1,2; Lin, Xiu-Kun1
刊名MOLECULES
2011-04-01
卷号16期号:4页码:2796-2801
关键词Polyketide Chromone Indole Alkaloid Mosher Exophiala Pisciphila
ISSN号1420-3049
DOI10.3390/molecules16042796
文献子类Article
英文摘要A new polyketide compound 1 and a new naturally occurring chromone derivative 2, along with two known indole alkaloids 3-4 were characterized from the ethyl acetate extract of a soil-derived fungal strain, Exophiala pisciphila PHF-9. The structures of compounds 1-4 were established by detailed spectroscopic analysis and comparison with literature data. The absolute configuration of 1 was determined by a modified Mosher's method. Compound 1 exhibited moderate cytotoxicity against A-549, Hela, PANC-28 and BEL-7402 cell lines.; A new polyketide compound 1 and a new naturally occurring chromone derivative 2, along with two known indole alkaloids 3-4 were characterized from the ethyl acetate extract of a soil-derived fungal strain, Exophiala pisciphila PHF-9. The structures of compounds 1-4 were established by detailed spectroscopic analysis and comparison with literature data. The absolute configuration of 1 was determined by a modified Mosher's method. Compound 1 exhibited moderate cytotoxicity against A-549, Hela, PANC-28 and BEL-7402 cell lines.
学科主题Chemistry
URL标识查看原文
语种英语
WOS记录号WOS:000289236200005
公开日期2012-07-03
内容类型期刊论文
源URL[http://ir.qdio.ac.cn/handle/337002/11828]  
专题海洋研究所_实验海洋生物学重点实验室
作者单位1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
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Wang, Cui-Cui,Liu, Hai-Zhou,Liu, Ming,et al. Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila[J]. MOLECULES,2011,16(4):2796-2801.
APA Wang, Cui-Cui,Liu, Hai-Zhou,Liu, Ming,Zhang, Yu-Yan,Li, Tian-Tian,&Lin, Xiu-Kun.(2011).Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila.MOLECULES,16(4),2796-2801.
MLA Wang, Cui-Cui,et al."Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila".MOLECULES 16.4(2011):2796-2801.
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