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	Antitumor Peptides from Marine Organisms
	Zheng, Lan-Hong3; Wang, Yue-Jun3; Sheng, Jun3; Wang, Fang3; Zheng, Yuan3; Lin, Xiu-Kun1,2; Sun, Mi3
刊名	MARINE DRUGS
	2011-10-01
卷号	9期号:10页码:1840-1859
关键词	Antitumor Peptides Marine Organisms
ISSN号	1660-3397
DOI	10.3390/md9101840
文献子类	Review
英文摘要	The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new antitumor agents in the field of the development of marine bioactive substances. In this review, the progress on studies of antitumor peptides from marine sources is provided. The biological properties and mechanisms of action of different marine peptides are described; information about their molecular diversity is also presented. Novel peptides that induce apoptosis signal pathway, affect the tubulin-microtubule equilibrium and inhibit angiogenesis are presented in association with their pharmacological properties. It is intended to provide useful information for further research in the fields of marine antitumor peptides.; The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new antitumor agents in the field of the development of marine bioactive substances. In this review, the progress on studies of antitumor peptides from marine sources is provided. The biological properties and mechanisms of action of different marine peptides are described; information about their molecular diversity is also presented. Novel peptides that induce apoptosis signal pathway, affect the tubulin-microtubule equilibrium and inhibit angiogenesis are presented in association with their pharmacological properties. It is intended to provide useful information for further research in the fields of marine antitumor peptides.
学科主题	Pharmacology & Pharmacy
URL标识	查看原文
语种	英语
WOS记录号	WOS:000298928300008
公开日期	2012-07-03
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/11784]
专题	海洋研究所_实验海洋生物学重点实验室
作者单位	1.Capital Med Univ, Dept Pharmacol, Beijing 100069, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 3.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Zheng, Lan-Hong,Wang, Yue-Jun,Sheng, Jun,et al. Antitumor Peptides from Marine Organisms[J]. MARINE DRUGS,2011,9(10):1840-1859.
APA	Zheng, Lan-Hong.,Wang, Yue-Jun.,Sheng, Jun.,Wang, Fang.,Zheng, Yuan.,...&Sun, Mi.(2011).Antitumor Peptides from Marine Organisms.MARINE DRUGS,9(10),1840-1859.
MLA	Zheng, Lan-Hong,et al."Antitumor Peptides from Marine Organisms".MARINE DRUGS 9.10(2011):1840-1859.

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