Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility
	He, Xin 1; Yang, Jing2 ; Qiu, Ling 1; Feng, Dan 1; Ju, Feng 1; Tan, Lu 1; Li, Yu-Zhi 1; Gu, Yu-Cheng 3; Zhang, Zhen 1; Guo, Da-Le 1
刊名	MOLECULES
	2019-01-02
卷号	24 期号:2 页码:8
关键词	Penicillium crustosum Isaria cicadae thiodiketopiperazines Mosher analysis ECD calculation gastrointestinal motility
ISSN号	1420-3049
英文摘要	Three new thiodiketopiperazines (1-3), along with two known analogues (4 and 5), were isolated from the fermentation broth of Penicillium crustosum. Their structures were elucidated through extensive spectroscopic analysis and the absolute configurations of new compounds were determined by Mosher ester analysis and calculated ECD spectra. Compound 4 and 5 have the activity to promote the gastrointestinal motility of zebrafish via acting on the cholinergic nervous system.
资助项目	Sichuan Provincial Youth Science and Technology Innovation Team[2016TD0006] ; Sichuan Provincial Youth Science and Technology Innovation Team[2015TD0028] ; China Postdoctoral Science Foundation[2017M622985]
语种	英语
资助机构	Sichuan Provincial Youth Science and Technology Innovation Team ; China Postdoctoral Science Foundation
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/64427]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Guo, Da-Le; Deng, Yun
作者单位	1.Chengdu Univ Tradit Chinese Med, Breeding Base Systemat Res Dev & Utilizat Chinese, Key Lab Standardizat Chinese Herbal Med, Minist Educ,State Key Lab,Sch Pharm, Chengdu 611137, Sichuan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 3.Syngenta Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England
推荐引用方式 GB/T 7714	He, Xin,Yang, Jing,Qiu, Ling,et al. Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility[J]. MOLECULES,2019,24(2):8.
APA	He, Xin.,Yang, Jing.,Qiu, Ling.,Feng, Dan.,Ju, Feng.,...&Deng, Yun.(2019).Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility.MOLECULES,24(2),8.
MLA	He, Xin,et al."Thiodiketopiperazines Produced by Penicillium crustosum and Their Activities to Promote Gastrointestinal Motility".MOLECULES 24.2(2019):8.