Live attenuated Salmonella typhimurium vaccines delivering SaEsxA and SaEsxB via type III secretion system confer protection against Staphylococcus aureus infection.

	Live attenuated Salmonella typhimurium vaccines delivering SaEsxA and SaEsxB via type III secretion system confer protection against Staphylococcus aureus infection.
	Deng, Jian; Xu, Chen; Zhang, Bao-zhong; Lin, Qiubin; Yu, Bin; Arya, Smriti; Yuen, Kwok-Yung; Huang, Jian-Dong
刊名	BMC INFECTIOUS DISEASES
	2018
文献子类	期刊论文
英文摘要	Background: Staphylococcus aureus (S. aureus) causes a wide range of infectious diseases in human and animals. The emergence of antibiotic-resistant strains demands novel strategies for prophylactic vaccine development In this study, live attenuated S. enterica subsp. enterica serotype Typhimurium (S. Typhimurium) vaccine against S. aureus infection was developed, in which Salmonella Pathogenesis Island-1 Type 3 Secretion System (SPI-1 T3SS) was employed to deliver SaEsxA and SaEsxB, two of ESAT-6-like (Early Secreted Antigenic Target-6) virulence factors of S. aureus.
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/13423]
专题	合成所
推荐引用方式 GB/T 7714	Deng, Jian,Xu, Chen,Zhang, Bao-zhong,et al. Live attenuated Salmonella typhimurium vaccines delivering SaEsxA and SaEsxB via type III secretion system confer protection against Staphylococcus aureus infection.[J]. BMC INFECTIOUS DISEASES,2018.
APA	Deng, Jian.,Xu, Chen.,Zhang, Bao-zhong.,Lin, Qiubin.,Yu, Bin.,...&Huang, Jian-Dong.(2018).Live attenuated Salmonella typhimurium vaccines delivering SaEsxA and SaEsxB via type III secretion system confer protection against Staphylococcus aureus infection..BMC INFECTIOUS DISEASES.
MLA	Deng, Jian,et al."Live attenuated Salmonella typhimurium vaccines delivering SaEsxA and SaEsxB via type III secretion system confer protection against Staphylococcus aureus infection.".BMC INFECTIOUS DISEASES (2018).