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	Improved quantification of amide proton transfer effect with direct saturation- and magnetization transfer-correction in a glioma rat model at 3 Tesla
	Wu Yin; Chen Yinsheng; Zhao Yiying; Yang Shasha; Zhao Jing; Chen Zhongping; Sun Phillip Zhe
	2018
会议日期	2018年
会议地点	巴黎
英文摘要	Quantification of in vivo APT effect with routine asymmetry analysis is problematic due to concomitant contributions. Herein, a steady-state CEST signal solution was utilized to estimate direct water saturation (DWS) to improve Z-spectral quantification in a pulsed-RF CEST imaging. Specifically, APT effect was measured from the DWS and magnetization transfer (MT)-corrected CEST signals in glioma rat brains post-chemoradiotherapy at 3 Tesla. The proposed method revealed significant APT signal difference among regions of control (3.13±0.38%), necrosis (3.95±0.31%) and tumor (4.56±0.34%), consistent with histological observations and superior than routine asymmetry analysis.
URL标识	查看原文
内容类型	会议论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/14570]
专题	深圳先进技术研究院_医工所
推荐引用方式 GB/T 7714	Wu Yin,Chen Yinsheng,Zhao Yiying,et al. Improved quantification of amide proton transfer effect with direct saturation- and magnetization transfer-correction in a glioma rat model at 3 Tesla[C]. 见:. 巴黎. 2018年.

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