Development of an intravascular ultrasound elastography based on a dual-element transducer.

	Development of an intravascular ultrasound elastography based on a dual-element transducer.
	Ma, Teng; Shung, K. Kirk; Huang, Chih-Chung; Shih, Cho-Chiang; Chen, Pei-Yu; Zhou, Qifa
刊名	ROYAL SOCIETY OPEN SCIENCE
	2018
文献子类	期刊论文
英文摘要	The ability to measure the elastic properties of plaques and vessels would be useful in clinical diagnoses, particularly for detecting a vulnerable plaque. This study demonstrates the feasibility of the combination of intravascular ultrasound (IVUS) and acoustic radiation force elasticity imaging for detecting the distribution of stiffness within atherosclerotic arteries ex vivo. A dual-frequency IVUS transducer with two elements was used to induce the propagation ofthe shear wave (by the 8.5MHz pushing element) which could be simultaneously monitored by the 31MHz imaging element. The wave-amplitude image and the wave-velocity image were reconstructed by measuring the peak displacement and wave velocity of shear wave propagation, respectively. System performance was verified using gelatin phantoms. The phantom results demonstrate that the stiffness differences of shear modulus of 1.6 kPa can be distinguished through the wave-amplitude and wave-velocity images. The stiffness distributions of the atherosclerotic aorta from a rabbit were obtained, for which the values of peak displacement and the shear wave velocity were 3.7 +/- 1.2 mu m and 0.38 +/- 0.19 m s(-1) for the lipid-rich plaques, and 1.0 +/- 0.2 mu m and 3.45 +/- 0.45 m s(-1) for the arterial walls, respectively. These results indicate that IVUS elasticity imaging can be used to distinguish the elastic properties of plaques and vessels.
URL标识	查看原文
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/14326]
专题	深圳先进技术研究院_医工所
推荐引用方式 GB/T 7714	Ma, Teng,Shung, K. Kirk,Huang, Chih-Chung,et al. Development of an intravascular ultrasound elastography based on a dual-element transducer.[J]. ROYAL SOCIETY OPEN SCIENCE,2018.
APA	Ma, Teng,Shung, K. Kirk,Huang, Chih-Chung,Shih, Cho-Chiang,Chen, Pei-Yu,&Zhou, Qifa.(2018).Development of an intravascular ultrasound elastography based on a dual-element transducer..ROYAL SOCIETY OPEN SCIENCE.
MLA	Ma, Teng,et al."Development of an intravascular ultrasound elastography based on a dual-element transducer.".ROYAL SOCIETY OPEN SCIENCE (2018).