Epigenetic divergence of key genes associated with water temperature and salinity in a highly invasive model ascidian

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 中国科学院环境生物技术重点实验室

	Epigenetic divergence of key genes associated with water temperature and salinity in a highly invasive model ascidian
	Zhan, Aibin; Pu, Chuanliang
刊名	BIOLOGICAL INVASIONS
	2017-07-01
卷号	19 期号:7 页码:2015-2028
关键词	Ascidian Biological Invasion Dna Methylation Environmental Factor Epgenetics Invasive Species Local Adaptation
英文摘要	Invasive species offer good models for studying mechanisms of response to rapid changing environments in the wild. DNA methylation is considered to be one of crucial drivers for rapid local adaptation. However, the extent of epigenetic variation and the factors driving such variation remain largely unexplored in biological invasions. Here we used direct bisulfite sequencing to investigate DNA methylation patterns of five key genes corresponding to two important environmental factors in marine ecosystems, water temperature and salinity, in a model invasive ascidian Ciona robusta (=C. intestinalis spA). Our results clearly showed that DNA methylation mainly occurred in gene bodies, rather than promoters, at regions with low values of CpG O/E. We detected significant variation of DNA methylation among populations in two genes (heat shock protein 90 and Na+-K+-2Cl(-) cotransporter). Interestingly, significant correlation was detected between methylation levels and the two environmental factors at some CpGs in these two genes. When the data of all CpGs was subjected to principal component analysis, individuals were assigned back to their population orgins. All the results suggest that environmental factors likely contribute, at least partially, to the observed DNA methylation variation. Such variation, either by some loci alone or through gene networks, might be involved in rapid local adaptation during biological invasions.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/39631]
专题	生态环境研究中心_中国科学院环境生物技术重点实验室
推荐引用方式 GB/T 7714	Zhan, Aibin,Pu, Chuanliang. Epigenetic divergence of key genes associated with water temperature and salinity in a highly invasive model ascidian[J]. BIOLOGICAL INVASIONS,2017,19(7):2015-2028.
APA	Zhan, Aibin,&Pu, Chuanliang.(2017).Epigenetic divergence of key genes associated with water temperature and salinity in a highly invasive model ascidian.BIOLOGICAL INVASIONS,19(7),2015-2028.
MLA	Zhan, Aibin,et al."Epigenetic divergence of key genes associated with water temperature and salinity in a highly invasive model ascidian".BIOLOGICAL INVASIONS 19.7(2017):2015-2028.