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	An ecological analysis of PM2.5 concentrations and lung cancer mortality rates in China
	Fu J. Y.; Jiang, D.; Lin, G.; Liu, K.; Wang, Q.
	2015
关键词	particulate air-pollution geographically weighted regression health exposure
英文摘要	Objective: To explore the association between Particulate Matter (PM)(2.5) (particles with an aerodynamic diameter less than 2.5 mu m) and lung cancer mortality rates and to estimate the potential risk of lung cancer mortality related to exposure to high PM2.5 concentrations. Design: Geographically weighted regression was performed to evaluate the relation between PM2.5 concentrations and lung cancer mortality for males, females and for both sexes combined, in 2008, based on newly available long-term data. Lung cancer fatalities from long-term exposure to PM2.5 were calculated according to studies by Pope III et al and the WHO air quality guidelines (AQGs). Setting: 31 provinces in China. Results: PM2.5 was associated with the lung cancer mortality of males, females and both sexes combined, in China, although there were exceptions in several regions, for males and females. The number of lung cancer fatalities calculated by the WHO AQGs ranged from 531 036 to 532 004, whereas the number calculated by the American Cancer Society (ACS) reached 614 860 after long-term (approximately 34 years) exposure to PM2.5 concentrations since 2008. Conclusions: There is a positive correlation between PM2.5 and lung cancer mortality rate, and the relationship between them varies across the entire country of China. The number of lung cancer fatalities estimated by ACS was closer to the actual data than those of the WHO AQGs. Therefore, the ACS estimate of increased risk of lung cancer mortality from long-term exposure to PM2.5 might be more applicable for evaluating lung cancer fatalities in China than the WHO estimate.
出处	Bmj Open
卷	5
期	11
语种	英语
ISSN号	2044-6055
DOI标识	10.1136/bmjopen-2015-009452
内容类型	SCI/SSCI论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/43526]
专题	资源利用与环境修复重点实验室_资源地理与国土资源研究室_SCI/SSCI期刊论文
推荐引用方式 GB/T 7714	Fu J. Y.,Jiang, D.,Lin, G.,et al. An ecological analysis of PM2.5 concentrations and lung cancer mortality rates in China. 2015.

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