QQ客服 官方微博 反馈留言

	One-step process for preparation of polar/non-polar copolymerized stationary phases by using surface horizontal polymerization; 基于表面水平聚合的极性/非极性共聚固定相制备
	Guo ZM(郭志谋) ; Liang T(梁图) ; Cai XM(蔡晓明) ; Ceng J(曾静) ; Wang CR(王超然) ; Liang XM(梁鑫淼)
	2009-10-18
会议名称	24th international symposium on microscale bioseparations
会议日期	2009-10-18
会议地点	中国
其他题名	基于表面水平聚合的极性/非极性共聚固定相制备
页码	272/1
通讯作者	梁鑫淼
中文摘要	reversed-phase liquid chromatography (rplc) is the most popular chromatographic mode for the separation of a wide variety of compounds. the traditional alkyl stationary phases for rplc primarily complement hydrophobic interaction, while the polar interactions are limited. polar rplc stationary phases are developed to enhance the polar interactions in the rp separation of polar compounds. so far, there are two main approaches, e.g. polar embeded and polar endcapped, for the introduction of polar groups in rplc stationary phases. 1 herein, a new approach with one-step process for preparation of polar stationary phases for rplc was proposed. in this approach, the mixture of polar silane (e. g. 3-chloridepropyltrichlorosilane) and non-polar silane (e. g. n-octadecyltrichlosilane) are copolymerized on the silica surface to afford the “polar/non-polar copolymerized stationary phase” (figure 1) by using horizontal polymerization silanization method, which was introduced by wirth and coworkers. 2 this new approach is facile and flexible. the types and ratios of the polar and non-polar silanes can be used for preparation of well designed stationary phases. the polar/non-polar copolymerized stationary phases demonstrated good separation efficiency and selectivity in the separation of test standards, tryptic digests of bovine serum albumin and several kinds of traditional chinese medicines (tcms).
会议主办者	中国科学院大连化物所
学科主题	物理化学
语种	中文
内容类型	会议论文
源URL	[http://159.226.238.44/handle/321008/113892]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
推荐引用方式 GB/T 7714	Guo ZM,Liang T,Cai XM,et al. One-step process for preparation of polar/non-polar copolymerized stationary phases by using surface horizontal polymerization, 基于表面水平聚合的极性/非极性共聚固定相制备[C]. 见:24th international symposium on microscale bioseparations. 中国. 2009-10-18.

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。