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	Flow control for microfluidic system with liquid nitrogen valve
	Sun LL(孙良亮) ; Zhu GJ(朱贵杰) ; Liang Z(梁振) ; Zhang WB(张维冰) ; Zhang LH(张丽华) ; Zhang YK(张玉奎)
	2009-10-19
会议名称	the 24th msb 2009
会议日期	2009-10-19
会议地点	中国
页码	178/1
通讯作者	张丽华
中文摘要	to achieve multiple functions of microfluidic systems, microvalves are indispensable units to control fluid paths, close/open specific sections, and measure reagent volumes. although various valves have been developed, and shown good properties on microchips, not only the design but also the fabrication are relatively complex. in this work, a novel liquid nitrogen valve was designed and applied in microfluidic chip for flow control, according to the fast freezing and thawing properties of liquid nitrogen. by dropping liquid nitrogen on microchip surface, fluid in microchannels was frozen, and thus the flow stopped flowing by closing the valve. after heating by an electric blower, the frozen fluid was thawed, and with valve open, fluid began to remove. our experimental results show that the time required to open and close the valve is 3.7 s and 1.1 s, respectively, and the rsds of the open/close time in five consecutive operation are 5.4% and 7.5%, respectively. furthermore, the valve could resist pressures up to 33 mpa. all these results demonstrated the facile valve could be successfully used on microfluidic chips for flow control. in addition, the valve is an green valve, without any pollution to environment. therefore, such liquid nitrogen valves are of the advantages including fast switching, good endurance to high pressure, simple, green and low cost, making it promising for flow control in microfluidic systems.
会议主办者	大连化物所
学科主题	物理化学
语种	中文
内容类型	会议论文
源URL	[http://159.226.238.44/handle/321008/113610]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
推荐引用方式 GB/T 7714	Sun LL,Zhu GJ,Liang Z,et al. Flow control for microfluidic system with liquid nitrogen valve[C]. 见:the 24th msb 2009. 中国. 2009-10-19.

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