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	Versatile t-1-based chemical analysis platform using fe3+/fe2+ interconversion
	Chen, Yiping1,2; Yin, Binfeng1,2; Dong, Mingling1,2; Xianyu, Yunlei1,2; Jiang, Xingyu1,2,3
刊名	Analytical chemistry
	2018-01-16
卷号	90期号:2页码:1234-1240
ISSN号	0003-2700
DOI	10.1021/acs.analchem.7b03961
通讯作者	Jiang, xingyu(xingyujiang@nanoctr.cn)
英文摘要	We report a versatile analytical platform for assaying multiple analytes relying on changes in longitudinal relaxation time (t-1) as a result of fe3+/fe2+ interconversion. the t-1 of water protons in fe3+ aqueous solution differs significantly from that of fe2+, allowing for the development of a generally applicable trbased assay since many redox reactions enable the interconversion between fe' and fe3+ that can result in the change of ti. compared with conventional magnetic biosensors, this t-1-based assay is free of magnetic nanoparticles (mnps), and the stability of t-1 based assay is better than conventional magnetic sensors that suffer from nonspecific adsorption and aggregation of mnps. this t-1-based assay simultaneously enables "one-step mixing" assays (such as saliva sugar) and "multiple-washing" immunoassays with good stability and sensitivity, offering a promising platform for convenient, stable, and versatile biomedical analysis
WOS关键词	MAGNETIC-RESONANCE ; ULTRASENSITIVE DETECTION ; ONE-STEP ; NANOPARTICLES ; RELAXATION ; SEPARATION ; PATHOGENS ; PARTICLES ; CHEMISTRY ; PROTEINS
WOS研究方向	Chemistry
WOS类目	Chemistry, Analytical
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000423011600029
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2177889
专题	高能物理研究所
通讯作者	Jiang, Xingyu
作者单位	1.Beijing Engn Res Ctr BioNanotechnol, 11 Beiyitiao, Beijing 100190, Peoples R China 2.Natl Ctr NanoSci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biol Effects Nanomat & Nanosafety, 11 Beiyitiao, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, 19 A YuQuan Rd, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Chen, Yiping,Yin, Binfeng,Dong, Mingling,et al. Versatile t-1-based chemical analysis platform using fe3+/fe2+ interconversion[J]. Analytical chemistry,2018,90(2):1234-1240.
APA	Chen, Yiping,Yin, Binfeng,Dong, Mingling,Xianyu, Yunlei,&Jiang, Xingyu.(2018).Versatile t-1-based chemical analysis platform using fe3+/fe2+ interconversion.Analytical chemistry,90(2),1234-1240.
MLA	Chen, Yiping,et al."Versatile t-1-based chemical analysis platform using fe3+/fe2+ interconversion".Analytical chemistry 90.2(2018):1234-1240.

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