| Toxicity and transformation of graphene oxide and reduced graphene oxide in bacteria biofilm | |
| Guo, Zhiling1,2; Xie, Changjian2; Zhang, Peng2; Zhang, Junzhe1; Wang, Guohua2; He, Xiao2; Ma, Yuhui2; Zhao, Bin1; Zhang, Zhiyong2 | |
| 刊名 | Science of the total environment
 |
| 2017-02-15 | |
| 卷号 | 580页码:1300-1308 |
| 关键词 | Graphene oxide Reduced graphene oxide Biofilm Toxicity Transformation |
| ISSN号 | 0048-9697 |
| DOI | 10.1016/j.scitotenv.2016.12.093 |
| 通讯作者 | Zhang, peng(pengzhang@ihep.ac.cn) ; Zhao, bin(binzhao@rcees.ac.cn) ; Zhang, zhiyong(zhangzhy@ihep.ac.cn) |
| 英文摘要 | Impact of graphene based material (gnms) on bacteria biofilm has not been well understood yet in this study, we compared the impact of graphene oxide (go) and reduced graphene oxide (rgo) on biofilm formation and development in luria-bertani (lb) medium using escherichia coli and staphylococcus aureus as models. go significantly enhanced the cell growth, biofilm formation, and biofilm development even up to a concentration of 500 mg/l. in contrast, rgo (>= 50 mg/l) strongly inhibited cell growth and biofilm formation. however, the inhibitory effects of rgo (50 mg/l and 100 mg/l) were attenuated in the mature phase (>24 h) and eliminated at 48 h. go at 250 mg/l decreased the reactive oxygen species (ros) levels in biofilm and extracellular region at mature phase. ros levels were significantly increased by rgo at early phase, while they returned to the same levels as control at mature phase. these results suggest that oxidative stress contributed to the inhibitory effect of rgo on bacterial biofilm. we further found that supplement of extracellular polymeric substances (eps) in the growth medium attenuated the inhibitory effect of rgo on the growth of developed biofilm. xps results showed that rgo were oxidized to go which can enhance the bacterial growth. we deduced that the elimination of the toxicity of rgo at mature phase was contributed by eps protection and the oxidation of rgo. this study provides new insights into the interaction of gnms with bacteria biofilm. (c) 2016 elsevier b.v. all rights reserved. |
| WOS关键词 | WALLED CARBON NANOTUBES ; ANTIBACTERIAL ; NANOSHEETS ; GROWTH ; OXIDATION ; SUSCEPTIBILITY ; NANOPARTICLES ; ANTIBIOTICS ; COMPOSITES ; RESISTANCE |
| WOS研究方向 | Environmental Sciences & Ecology |
| WOS类目 | Environmental Sciences |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCIENCE BV |
| WOS记录号 | WOS:000395353600127 |
| 内容类型 | 期刊论文 |
| URI标识 | http://www.corc.org.cn/handle/1471x/2176736 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Zhang, Peng; Zhao, Bin; Zhang, Zhiyong |
| 作者单位 | 1.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China 2.Chinese Acad Sci, Inst High Energy Phys, Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guo, Zhiling,Xie, Changjian,Zhang, Peng,et al. Toxicity and transformation of graphene oxide and reduced graphene oxide in bacteria biofilm[J]. Science of the total environment,2017,580:1300-1308. |
| APA | Guo, Zhiling.,Xie, Changjian.,Zhang, Peng.,Zhang, Junzhe.,Wang, Guohua.,...&Zhang, Zhiyong.(2017).Toxicity and transformation of graphene oxide and reduced graphene oxide in bacteria biofilm.Science of the total environment,580,1300-1308. |
| MLA | Guo, Zhiling,et al."Toxicity and transformation of graphene oxide and reduced graphene oxide in bacteria biofilm".Science of the total environment 580(2017):1300-1308. |
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