Implantable CMOS neuro-stimulus chip for visual prosthesis

CORC > 半导体研究所 > 中国科学院半导体研究所 > 集成光电子学国家重点实验室

	Implantable CMOS neuro-stimulus chip for visual prosthesis
	Guo K; Zhang X; Huang BJ
刊名	science china-information sciences
	2011
卷号	54 期号:4 页码:898-908
关键词	biomedical microelectronics visual prosthesis functional electrical stimulation acute animal experiment electrical evoked potential (EEP) test RETINAL PROSTHESIS STIMULATION DEVICE BLIND
ISSN号	1674-733x
通讯作者	zhang, x, chinese acad sci, inst semicond, state key lab integrated optoelect, beijing 100083, peoples r china. zhangxu@semi.ac.cn
学科主题	光电子学
收录类别	SCI
资助信息	national natural science foundation of china [60776024, 60877035, 90820002]; national high-tech research & development program of china [2007aa04z329, 2007aa04z254]
语种	英语
公开日期	2011-07-05 ; 2011-07-15
附注	a prototype chip with 2x2 pixels for implanting in blind patients affected by outer retinal degeneration is presented in this paper. this visual prosthesis chip imitates the degenerated photoreceptor cells, senses the incident light and stimulates the remaining healthy layers of retina or optic nerve. each pixel integrates photodiode and stimulus pulse generator, converting the illumination on the eyes into 3-bit resolution bi-phasic current pulses. on-chip charge cancellation modules are used to discharge each electrode site for tissue safety. the prototype chip is designed and fabricated in 0.18-mu m n-well cmos (complementary metal oxide semiconductor) 1p6m mix-signal process, with a +/- 2.5 v dual voltage supply. the functionality of the fabricated chip is demonstrated on anesthetized rabbits. neural responses in visual cortex are successfully evoked by the neuro-stimulus chip through an on-board trigger interface and flexible electrode.
内容类型	期刊论文
源URL	[http://ir.semi.ac.cn/handle/172111/20961]
专题	半导体研究所_集成光电子学国家重点实验室
推荐引用方式 GB/T 7714	Guo K,Zhang X,Huang BJ. Implantable CMOS neuro-stimulus chip for visual prosthesis[J]. science china-information sciences,2011,54(4):898-908.
APA	Guo K,Zhang X,&Huang BJ.(2011).Implantable CMOS neuro-stimulus chip for visual prosthesis.science china-information sciences,54(4),898-908.
MLA	Guo K,et al."Implantable CMOS neuro-stimulus chip for visual prosthesis".science china-information sciences 54.4(2011):898-908.