Altered gut microbiota associated with intestinal disease in grass carp (Ctenopharyngodon idellus)

doi:10.1007/s11274-018-2447-2

CORC > 武汉植物园 > 中国科学院武汉植物园

	Altered gut microbiota associated with intestinal disease in grass carp (Ctenopharyngodon idellus)
	Xiong, Fan 3,4,5; Zhang, Jing 3,4,5; Wang, Gui-Tang 3,4,5; Wu, Shan-Gong 3,4,5; Li, Wen-Xiang 3,4,5; Ngoc Tuan Tran 1,2,3,4,5
刊名	WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
	2018-06-01
卷号	34 期号:6 页码:9
关键词	Grass carp Intestinal inflammation Enteritis Gut microbiota Structure and function 16S rRNA gene
ISSN号	0959-3993
DOI	10.1007/s11274-018-2447-2
英文摘要	Gut microbiota plays a crucial importance in their host. Disturbance of the microbial structure and function is known to be associated with inflammatory intestinal disorders. Enteritis is a significant cause of high mortality in fish species, including grass carp (Ctenopharyngodon idellus). Study regarding the association between microbial alternations and enteritis in grass carp is still absent. In this study, changes in the gut microbiota of grass carp suffering from enteritis were investigated using NGS-based 16S rRNA sequencing. Six healthy and ten abnormal fish (showing reddening anus, red odiferous fluid accumulating in the abdominal capacity, and flatulence and haemorrhage in the intestine) were collected from a fish farm in Huanggang Fisheries Institute (Hubei, China). Our results revealed that the diversity, structure, and function of gut microbiota were significantly different between diseased and healthy fish (P < 0.05). Particularly, members of the genera Dechloromonas, Methylocaldum, Planctomyces, Rhodobacter, Caulobacter, Flavobacterium, and Pseudomonas were significantly increased in diseased fish compared with that in healthy fish (P < 0.05). Predicted function indicated that microbiota significantly changed the specific metabolic pathways (related to amino acid metabolism, xenobiotics biodegradation and metabolism, and carbohydrate metabolism) in diseased fish (P < 0.05). Taken together, our findings point out the association between changes of the gut microbiota and enteritis in grass carp, which provide basic information useful for diagnoses, prevention, and treatment of intestinal diseases occurring in cultured fish.
资助项目	Chinese Academy of Sciences (CAS) ; National Natural Science Foundation of China[31372571] ; National Natural Science Foundation of China[31272706] ; earmarked fund for China Agriculture Research System[CARS-45-15]
WOS研究方向	Biotechnology & Applied Microbiology
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000433166300002
内容类型	期刊论文
源URL	[http://202.127.146.157/handle/2RYDP1HH/5332]
专题	中国科学院武汉植物园
通讯作者	Wu, Shan-Gong
作者单位	1.Shantou Univ, Guangdong Prov Key Lab Marine Biol, Shantou 515063, Peoples R China 2.Shantou Univ, Marine Biol Inst, Shantou 515063, Peoples R China 3.Chinese Acad Sci, Inst Hydrobiol, Minist Agr, Key Lab Aquaculture Dis Control, Wuhan, Hubei, Peoples R China 4.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan, Hubei, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Xiong, Fan,Zhang, Jing,Wang, Gui-Tang,et al. Altered gut microbiota associated with intestinal disease in grass carp (Ctenopharyngodon idellus)[J]. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,2018,34(6):9.
APA	Xiong, Fan,Zhang, Jing,Wang, Gui-Tang,Wu, Shan-Gong,Li, Wen-Xiang,&Ngoc Tuan Tran.(2018).Altered gut microbiota associated with intestinal disease in grass carp (Ctenopharyngodon idellus).WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,34(6),9.
MLA	Xiong, Fan,et al."Altered gut microbiota associated with intestinal disease in grass carp (Ctenopharyngodon idellus)".WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY 34.6(2018):9.