Surface radical chain-transfer reaction in deep eutectic solvents for preparation of silica-grafted stationary phases in hydrophilic interaction chromatography

doi:10.1016/j.talanta.2017.07.038

CORC > 兰州化学物理研究所 > 中国科学院兰州化学物理研究所 > 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室

	Surface radical chain-transfer reaction in deep eutectic solvents for preparation of silica-grafted stationary phases in hydrophilic interaction chromatography
	Yang BB(杨贝贝)1,2; Qiu HD(邱洪灯); Guan M(关明); Qiu HD(邱洪灯)1,2 ; Cai TP(蔡天培)1; Li Z(李湛)1; Guan M(关明)2
刊名	Talanta
	2017
卷号	175 页码:256-263
关键词	Dess Homopolymerization And Copolymerization Surface Radical Chain-transfer Reaction Stationary Phase Hydrophilic Interaction Chromatography
ISSN号	0039-9140
DOI	10.1016/j.talanta.2017.07.038
英文摘要	In this paper, deep eutectic solvents (DESs) were firstly used as new and green solvents for the preparation of polymer-grafted silica stationary phases. 1-Vinylimidazole and acrylic acid were homopolymerized and copolymerized on silica via surface radical chain-transfer reaction in the DESs. Three stationary phases including poly(1-vinylimidazole)-, poly(acrylic acid)-, poly(1-vinylimidazole-co-acrylic acid)-grafted silica were obtained and characterized by elemental analysis and Fourier transform infrared spectroscopy. Their hydrophilic interaction chromatographic properties were investigated for separation of nucleosides, nucleobases, saccharides and amino acids. The retention changes of nucleosides and nucleobases on these columns were investigated under different chromatographic conditions including acetonitrile content, salt concentration, pH of mobile phase and column temperature. The repeatability of these columns was also investigated. The results demonstrate that DESs can be used as new media for the synthesis of silica-based stationary phases by homopolymerization and copolymerization on the surface of porous silica particles.
学科主题	分析化学与药物化学
资助项目	药物分离材料研究组
语种	英语
WOS记录号	WOS:000412033100034
资助机构	NSFC (No. 21475142;21465023;21675164);the funds for Distinguished Young Scientists of Gansu (1506RJDA281);the “Hundred Talents Program”;the top priority program of “One-Three-Five” Strategic Planning of Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.licp.ac.cn/handle/362003/22226]
专题	兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
通讯作者	Qiu HD(邱洪灯); Guan M(关明)
作者单位	1.CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou 730000, China 2.Laboratory on Pollution Monitoring and Control, College of Chemistry and Chemical Engineering, Xinjiang Normal University, Urumqi 830054, China
推荐引用方式 GB/T 7714	Yang BB,Qiu HD,Guan M,et al. Surface radical chain-transfer reaction in deep eutectic solvents for preparation of silica-grafted stationary phases in hydrophilic interaction chromatography[J]. Talanta,2017,175:256-263.
APA	Yang BB.,邱洪灯.,关明.,Qiu HD.,Cai TP.,...&Guan M.(2017).Surface radical chain-transfer reaction in deep eutectic solvents for preparation of silica-grafted stationary phases in hydrophilic interaction chromatography.Talanta,175,256-263.
MLA	Yang BB,et al."Surface radical chain-transfer reaction in deep eutectic solvents for preparation of silica-grafted stationary phases in hydrophilic interaction chromatography".Talanta 175(2017):256-263.