Microwave aqueous synthesis of hydroxyapatite bilayer coating on magnesium alloy for orthopedic application

doi:10.1016/j.cej.2016.10.043

	Microwave aqueous synthesis of hydroxyapatite bilayer coating on magnesium alloy for orthopedic application
	Shen, Sibo 1,2; Cai, Shu 1; Li, Yan 1; Ling, Rui 1; Zhang, Feiyang 1; Xu, Guohua 3; Wang, Fengwu 1
刊名	Chemical Engineering Journal
	2017
卷号	309 页码:278-287
ISSN号	13858947
DOI	10.1016/j.cej.2016.10.043
英文摘要	Magnesium and magnesium alloys as promising biodegradable implants gain increasing interest. To improve their corrosion resistance and cytocompatibility, hydroxyapatite (HA) coatings with double-layer structure were synthesized on magnesium alloy through a rapid microwave aqueous chemical route. The coating prepared with microwave heating time of 10 min consisted of cotton-like HA as the surface layer and strip-like HA as the bottom layer, and the coating thickness was ∼10.0 μm. The growth kinetic, electrochemical property, degradation, mineralization and cytocompatibility of HA coated and naked magnesium alloys were investigated. Potentiodynamic polarization test demonstrated that corrosion current density of HA coated magnesium alloy prepared with microwave heating time of 10 min was ∼100 times lower than that of the naked counterpart. Immersion test indicated that the strip-like HA layer with thickness of ∼7.7 μm and low solubility endowed magnesium alloy with initial-stage protection; the nano-scale cotton-like HA layer exhibited high HA mineralization capacity. The mineralized layer reached ∼12.7 μm in thickness after 24 days’ immersion, eventually integrated with the original HA bilayer coating, providing favorable long-term protection for magnesium alloy. Moreover, HA coated magnesium alloy prepared with microwave heating time of 10 min enhanced osteoblast proliferation than the naked counterpart. These attractive results indicated that this HA bilayer coating is a potential protective coating on biodegradable magnesium and magnesium alloys for orthopedic application. © 2016 Elsevier B.V.
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/25662]
专题	中国科学院上海硅酸盐研究所
作者单位	1.Key Laboratory for Advanced Ceramics and Machining Technology of Ministry of Education, Tianjin University, Tianjin; 300072, China; 2.Center for Electron Microscopy, Institute for New Energy Materials & Low-Carbon Technologies, Tianjin University of Technology, Tianjin; 300384, China; 3.Shanghai Changzheng Hospital, Shanghai; 200003, China
推荐引用方式 GB/T 7714	Shen, Sibo,Cai, Shu,Li, Yan,et al. Microwave aqueous synthesis of hydroxyapatite bilayer coating on magnesium alloy for orthopedic application[J]. Chemical Engineering Journal,2017,309:278-287.
APA	Shen, Sibo.,Cai, Shu.,Li, Yan.,Ling, Rui.,Zhang, Feiyang.,...&Wang, Fengwu.(2017).Microwave aqueous synthesis of hydroxyapatite bilayer coating on magnesium alloy for orthopedic application.Chemical Engineering Journal,309,278-287.
MLA	Shen, Sibo,et al."Microwave aqueous synthesis of hydroxyapatite bilayer coating on magnesium alloy for orthopedic application".Chemical Engineering Journal 309(2017):278-287.