Nanoscale Functional Biomaterials for Cancer Theranostics

doi:10.2174/0929867324666170406111036

	Nanoscale Functional Biomaterials for Cancer Theranostics
	Liu, Linying 1,3; Li, Xiaoshuang 2; Chen, Lei 2; Zhang, Xin 1
刊名	CURRENT MEDICINAL CHEMISTRY
	2018
卷号	25 期号:25 页码:2987-3000
关键词	Nanomaterials biomaterials cancer imaging therapy theranostics liver tumor gliomatosis cerebri
ISSN号	0929-8673
DOI	10.2174/0929867324666170406111036
英文摘要	Nanomedicine is widely developed in recent years. In nanomedicine system, nanoscale and nanostructured functional materials are used to manipulate the human biology systems at the molecular level for cancer imaging and therapy. New nanostructure based functional materials consist of nanoscale liposomes, spheres, micelles, capsules, emulsion, suspension and phamacosomes. Several functional nanoparticles such as lipid-based and polymer-based materials are demonstrated to be drug delivery vehicles and imaging agents. These materials are biodegradable, biocompatible and have better bio-distribution, lower side effect and lower toxicity. In addition, hybrids with these materials coating provide uniquely electrical, optical and magnetic properties. This review discusses the research on the applications of functional materials, especially nanoparticles as imaging contrast agents, cancer therapeutic agents and multi-functional agents and this review focused on the theranostic integration treatments on liver cancer and brain cancer.
资助项目	National High Technology Research and Development Program[2016YFA0200303] ; Beijing Natural Science Foundation[2164071] ; National Natural Science Foundation of China[31522023] ; National Natural Science Foundation of China[51373177] ; National Natural Science Foundation of China[51573188] ; Beijing Municipal Science & Technology Commission[Z161100002616015] ; "Strategic Priority Research Program Research 5 Program" of the Chinese Academy of Sciences[XDA09030301-3]
WOS关键词	SOLID LIPID NANOPARTICLES ; DRUG-DELIVERY SYSTEM ; UP-CONVERSION NANOPARTICLES ; ULTRASOUND CONTRAST AGENTS ; COATED GOLD NANOPARTICLES ; IRON-OXIDE NANOPARTICLES ; TARGETED GENE DELIVERY ; HEPATOCELLULAR-CARCINOMA ; PHOTOTHERMAL THERAPY ; BIOMEDICAL APPLICATIONS
WOS研究方向	Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
语种	英语
出版者	BENTHAM SCIENCE PUBL LTD
WOS记录号	WOS:000447388100008
资助机构	National High Technology Research and Development Program ; Beijing Natural Science Foundation ; National Natural Science Foundation of China ; Beijing Municipal Science & Technology Commission ; "Strategic Priority Research Program Research 5 Program" of the Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.ipe.ac.cn/handle/122111/26189]
专题	中国科学院过程工程研究所
通讯作者	Chen, Lei; Zhang, Xin
作者单位	1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Navy Gen Hosp People Liberat Army, Dept Obstet & Gynecol, Beijing 100048, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Liu, Linying,Li, Xiaoshuang,Chen, Lei,et al. Nanoscale Functional Biomaterials for Cancer Theranostics[J]. CURRENT MEDICINAL CHEMISTRY,2018,25(25):2987-3000.
APA	Liu, Linying,Li, Xiaoshuang,Chen, Lei,&Zhang, Xin.(2018).Nanoscale Functional Biomaterials for Cancer Theranostics.CURRENT MEDICINAL CHEMISTRY,25(25),2987-3000.
MLA	Liu, Linying,et al."Nanoscale Functional Biomaterials for Cancer Theranostics".CURRENT MEDICINAL CHEMISTRY 25.25(2018):2987-3000.