The clinical application of a silicate-based wound dressing (DermFactor (R)) for wound healing after anal surgery: A randomized study

doi:10.1016/j.ijsu.2018.02.036

	The clinical application of a silicate-based wound dressing (DermFactor (R)) for wound healing after anal surgery: A randomized study
	Chen, Shuo ; Huan, Zhiguang 1; Zhang, Lin ; Chang, Jiang 1
刊名	INTERNATIONAL JOURNAL OF SURGERY
	2018
卷号	52 页码:237
关键词	Silicate-based wound dressing DermFactor (R) Anal surgery Wound healing
ISSN号	1743-9191
DOI	10.1016/j.ijsu.2018.02.036
英文摘要	Background: The object of the present study is to evaluate the feasibility of a silicate-based wound dressing (DermFactor (R)) in treating the wound of the patients after anorectal surgery. Materials and Methods: The present study included 328 patients who received anal surgery during the period from March 2013 to June 2015. The patients were randomized to 2 groups. The patients (n = 162) in the control group received conventional dressing therapy, while those in the observation group (n = 166) were treated with the combination of conventional dressing therapy and the use of a silicate-based wound dressing (DermFactor (R)). The wound healing outcomes of the two groups were observed and compared with each other by statistical analysis. Results: The average healing cycles in the observation group were 19.04 days for combined hemorrhoid patients, 23.72 days for anal fistula patients and 21.14 days for anal fissure patients, respectively, which were shorter than those in the control group (23.25 days for mixed hemorrhoid patients, 27.76 days for anal fistula patients and 24.32 days for fissure in ano patients, respectively). In addition, the observation group presented a significantly higher effective rate (80.4%) than the control group (70.4%). Conclusion: Our data demonstrated that the wound after anorectal surgery could be more effectively treated by using silicate-containing DermFactor (R).
学科主题	Surgery
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000430456700038
资助机构	This study was supported by The National Key Research and Development Program of China (2016YFC1100201) and Shanghai S&T Innovation Action Plan Project (16441904500). ; This study was supported by The National Key Research and Development Program of China (2016YFC1100201) and Shanghai S&T Innovation Action Plan Project (16441904500).
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/25038]
专题	中国科学院上海硅酸盐研究所
作者单位	1.Tianjin Union Med Ctr, Dept Anorectal Surg, 190 Jieyuan Rd, Tianjin 300121, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China
推荐引用方式 GB/T 7714	Chen, Shuo,Huan, Zhiguang,Zhang, Lin,et al. The clinical application of a silicate-based wound dressing (DermFactor (R)) for wound healing after anal surgery: A randomized study[J]. INTERNATIONAL JOURNAL OF SURGERY,2018,52:237, 240.
APA	Chen, Shuo,Huan, Zhiguang,Zhang, Lin,&Chang, Jiang.(2018).The clinical application of a silicate-based wound dressing (DermFactor (R)) for wound healing after anal surgery: A randomized study.INTERNATIONAL JOURNAL OF SURGERY,52,237.
MLA	Chen, Shuo,et al."The clinical application of a silicate-based wound dressing (DermFactor (R)) for wound healing after anal surgery: A randomized study".INTERNATIONAL JOURNAL OF SURGERY 52(2018):237.