Ca-Doped mesoporous SiO2/dental resin composites with enhanced mechanical properties, bioactivity and antibacterial properties

doi:10.1039/c7tb02864d

	Ca-Doped mesoporous SiO2/dental resin composites with enhanced mechanical properties, bioactivity and antibacterial properties
	Zhang, Yu 1; Huang, Cui 2,3; Chang, Jiang
刊名	JOURNAL OF MATERIALS CHEMISTRY B
	2018
卷号	6 期号:3 页码:477
ISSN号	2050-750X
DOI	10.1039/c7tb02864d
英文摘要	Ca-Doped mesoporous SiO2 (MCS) nanoparticles with diameter of 230 nm were synthesized by a sol-gel method with some modification. As inorganic fillers, they improved the mechanical properties of the resin composites with 5%, 10%, 20% addition (5RC, 10RC, 20RC). After soaking in the simulated oral fluid (SOF), the resin composites showed excellent activity in inducing apatite-mineralization. As mesoporous nanoparticles, they can be used as carriers for loading the antibacterial drug Ciprofloxacin hydrochloride (CiH). The antibacterial testing of the resin composites with MCS-CiH (5RC-CiH, 10RC-CiH, 20RC-CiH) demonstrated excellent antibacterial effects. The incorporation of Ca-doped mesoporous SiO2 into dental resin is a suitable approach for improving the properties of the dental resin, and the MCS/resin composites have the potential for application in preventing secondary-caries.
学科主题	Materials Science, bioMaterials
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000422871100013
资助机构	This work was supported by National Natural Science Foundation of China [grant numbers 81430012] and the International S&T cooperation project of Shanghai S&T innovation action plan [grant numbers 17540712300]. ; This work was supported by National Natural Science Foundation of China [grant numbers 81430012] and the International S&T cooperation project of Shanghai S&T innovation action plan [grant numbers 17540712300].
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/24543]
专题	中国科学院上海硅酸盐研究所
作者单位	1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Wuhan Univ, State Key Lab Breeding Base Basic Sci Stomatol Hu, Minist Educ, Sch & Hosp Stomatol, Wuhan 430079, Hubei, Peoples R China 4.Wuhan Univ, Key Lab Oral Biomed, Minist Educ, Sch & Hosp Stomatol, Wuhan 430079, Hubei, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Yu,Huang, Cui,Chang, Jiang. Ca-Doped mesoporous SiO2/dental resin composites with enhanced mechanical properties, bioactivity and antibacterial properties[J]. JOURNAL OF MATERIALS CHEMISTRY B,2018,6(3):477, 486.
APA	Zhang, Yu,Huang, Cui,&Chang, Jiang.(2018).Ca-Doped mesoporous SiO2/dental resin composites with enhanced mechanical properties, bioactivity and antibacterial properties.JOURNAL OF MATERIALS CHEMISTRY B,6(3),477.
MLA	Zhang, Yu,et al."Ca-Doped mesoporous SiO2/dental resin composites with enhanced mechanical properties, bioactivity and antibacterial properties".JOURNAL OF MATERIALS CHEMISTRY B 6.3(2018):477.