Nitrogen-doped carbon nanotubes decorated poly (L-Cysteine) as a novel, ultrasensitive electrochemical sensor for simultaneous determination of theophylline and caffeine

doi:10.1016/j.talanta.2017.08.076

	Nitrogen-doped carbon nanotubes decorated poly (L-Cysteine) as a novel, ultrasensitive electrochemical sensor for simultaneous determination of theophylline and caffeine
	Wang, Yingzi ; Ding, Yaping 1; Li, Li ; Hu, Ping 2
刊名	TALANTA
	2018
卷号	178 页码:449
关键词	Nitrogen-doped carbon nanotubes L-Cysteine Electrocheinical nanosensor Theophylline Caffeine
ISSN号	0039-9140
DOI	10.1016/j.talanta.2017.08.076
英文摘要	In present study, a novel and facile electrochemical sensor based on glassy carbon electrode (GCE) modified with nitrogen-doped carbon nanotubes (N-CNT) decorated with poly (L-Cysteine) (PLCY) were fabricated and applied for the simultaneous voltammetric determination of theophylline (THEO) and caffeine (CAF). The morphology and structure of multilayer film modified on the surface of glassy carbon electrode were investigated successfully by Scanning Electron Microscope (SEM), Transmission Electron Microscope (TEM) and Raman Spectroscopy. And the properties of the modified electrode were investigated by Chronocoulometry (CC), Cyclic Voltammetry (CV) and Differential Pulse Voltammetry (DPV) were utilized to investigate the electrochemical behavior of THEO and CAF on the composite film modified electrode. The results showed that the determination towards THEO and CAF can be operated at the same potential window with the oxidation current peak separated and non-interfering respectively. Compared to the bare GCE, the PLCY/N-CNT/GCE can signally meliorate the electrocatalytic activity towards the oxidation of THEO and CAF with a remarkably increase in the anodic peak currents of 495.94% and 465.48%. Under the optimal conditions, the fabrication multilayer film sensor had excellent performances in determination towards THEO and CAF with a wide linear dynamic range from 0.10 to 70.0 mu M and 0.40-140.0 mu M, low detection limit (S/N = 3) of 0.033 mu M and 0.20 mu M, respectively. The PLCY/N-CNT/GCE sensor also had advantages as easy-made, high-sensitivity, stability and reproducibility. Moreover, it was successfully used to analyze the THEO and CAF in green tee, oral theophylline sustained release tablets and energy drink sample with a satisfactory result.
学科主题	Chemistry, Analytical
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000416615500059
资助机构	The authors would like to thank the National Natural Science Foundation of China (Grant no. 21671132) and partly supported by Shanghai Key laboratory of High Temperature Superconductors, the Science and Technology Commission of Shanghai Municipality (Grant no. 14DZ2260700) for financial supports. ; The authors would like to thank the National Natural Science Foundation of China (Grant no. 21671132) and partly supported by Shanghai Key laboratory of High Temperature Superconductors, the Science and Technology Commission of Shanghai Municipality (Grant no. 14DZ2260700) for financial supports.
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/24529]
专题	中国科学院上海硅酸盐研究所
作者单位	1.Shanghai Univ, Dept Chem, Shanghai 200444, Peoples R China 2.Shanghai Univ, Shanghai Key Lab High Temp Superconductors, Shanghai 200444, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yingzi,Ding, Yaping,Li, Li,et al. Nitrogen-doped carbon nanotubes decorated poly (L-Cysteine) as a novel, ultrasensitive electrochemical sensor for simultaneous determination of theophylline and caffeine[J]. TALANTA,2018,178:449, 457.
APA	Wang, Yingzi,Ding, Yaping,Li, Li,&Hu, Ping.(2018).Nitrogen-doped carbon nanotubes decorated poly (L-Cysteine) as a novel, ultrasensitive electrochemical sensor for simultaneous determination of theophylline and caffeine.TALANTA,178,449.
MLA	Wang, Yingzi,et al."Nitrogen-doped carbon nanotubes decorated poly (L-Cysteine) as a novel, ultrasensitive electrochemical sensor for simultaneous determination of theophylline and caffeine".TALANTA 178(2018):449.