A novel approach based on magneto-electric torque sensor for non-contact biomarkers detection

CORC > 宁波材料技术与工程研究所 > 中国科学院宁波材料技术与工程研究所 > 2018专题

	A novel approach based on magneto-electric torque sensor for non-contact biomarkers detection
	Wu, Yuanzhao; Liu, Yiwei; Li, Fali; Zhou, Youlin; Ding, Jun; Li, Run-Wei
刊名	SENSORS AND ACTUATORS B-CHEMICAL
	2018
卷号	276 页码:540-544
关键词	Electrochemical Immunosensor Signal Amplification Mesoporous Carbon Alpha-fetoprotein Glucose-oxidase Immunoassay Biosensor Labels Electrochemiluminescence
英文摘要	A rapid system for the sensitive non-contact detection of proteins using actuated magnetic particle labels, which are measured with a magneto-electric torque (MET) sensor, is described. The system contains MET sensor with the cantilever of magnet and the "test strip" of magnetic beads has been fabricated. The performance of MET sensor is demonstrated using magnetic beads and its detection limit was found to be 0.05 mg/mL. Furthermore, the biomarkers of alpha-fetoprotein is captured by immobilized anti-AFP antibodies on the surface of the "test strip" and detected using magnetic beads labeled with anti-AFP antibodies. The detection limit was found to be 100 ng/mL. The low sample volume, high analytical performance and high detecting speed coupled with the inexpensive, mass-producible, hand-held MET biosensor make the system especially suitable for sensitive testing outside of laboratory environments.
学科主题	Materials Science ; Metallurgy & Metallurgical Engineering
语种	英语
公开日期	2018-12-04
内容类型	期刊论文
源URL	[http://ir.nimte.ac.cn/handle/174433/16975]
专题	2018专题
推荐引用方式 GB/T 7714	Wu, Yuanzhao,Liu, Yiwei,Li, Fali,et al. A novel approach based on magneto-electric torque sensor for non-contact biomarkers detection[J]. SENSORS AND ACTUATORS B-CHEMICAL,2018,276:540-544.
APA	Wu, Yuanzhao,Liu, Yiwei,Li, Fali,Zhou, Youlin,Ding, Jun,&Li, Run-Wei.(2018).A novel approach based on magneto-electric torque sensor for non-contact biomarkers detection.SENSORS AND ACTUATORS B-CHEMICAL,276,540-544.
MLA	Wu, Yuanzhao,et al."A novel approach based on magneto-electric torque sensor for non-contact biomarkers detection".SENSORS AND ACTUATORS B-CHEMICAL 276(2018):540-544.