Training to improve contrast sensitivity in amblyopia: correction of high-order aberrations

doi:10.1038/srep35702

CORC > 光电技术研究所 > 中国科学院光电技术研究所 > 自适应光学技术研究室（八室）

	Training to improve contrast sensitivity in amblyopia: correction of high-order aberrations
	Liao, Meng ; Zhao, Haoxing ; Liu, Longqian ; Li, Qian ; Dai, Yun ; Zhang, Yudong ; Zhou, Yifeng
刊名	SCIENTIFIC REPORTS
	2016
卷号	6
关键词	Wave-front Aberrations Anisometropic Amblyopia Juvenile Amblyopia Visual Performance Adaptive Optics Adult Amblyopia Defined Letters Vision Eyes Acuity
ISSN号	2045-2322
DOI	10.1038/srep35702
文献子类	J
英文摘要	Perceptual learning is considered a potential treatment for amblyopia even in adult patients who have progressed beyond the critical period of visual development because adult amblyopes retain sufficient visual plasticity. When perceptual learning is performed with the correction of high-order aberrations (HOAs), a greater degree of neural plasticity is present in normal adults and those with highly aberrated keratoconic eyes. Because amblyopic eyes show more severe HOAs than normal eyes, it is interesting to study the effects of HOA-corrected visual perceptual learning in amblyopia. In the present study, we trained twenty-six older child and adult anisometropic amblyopes while their HOAs were corrected using a real-time closed-loop adaptive optics perceptual learning system (AOPL). We found that adaptive optics (AO) correction improved the modulation transfer functions (MTFs) and contrast sensitivity functions (CSFs) of older children and adults with anisometropic amblyopia. When perceptual learning was performed with AO correction of the ocular HOAs, the improvements in visual function were not only demonstrated in the condition with AO correction but were also maintained in the condition without AO correction. Additionally, the learning effect with AO correction was transferred to the untrained visual acuity and fellow eyes in the condition without AO correction.
语种	英语
WOS记录号	WOS:000385585100001
资助机构	National Natural Science Foundation of China [61205202]
内容类型	期刊论文
源URL	[http://ir.ioe.ac.cn/handle/181551/8457]
专题	光电技术研究所_自适应光学技术研究室（八室）
作者单位	1.[Liao, Meng 2.Liu, Longqian 3.Li, Qian] Sichuan Univ, West China Hosp, Dept Optometry & Visual Sci, Chengdu, Peoples R China 4.[Liao, Meng 5.Liu, Longqian 6.Li, Qian] Sichuan Univ, West China Hosp, Dept Ophthalmol, Chengdu 610041, Peoples R China 7.[Zhao, Haoxing 8.Dai, Yun 9.Zhang, Yudong] Chinese Acad Sci, Inst Opt & Elect, Chengdu, Peoples R China 10.[Zhao, Haoxing
推荐引用方式 GB/T 7714	Liao, Meng,Zhao, Haoxing,Liu, Longqian,et al. Training to improve contrast sensitivity in amblyopia: correction of high-order aberrations[J]. SCIENTIFIC REPORTS,2016,6.
APA	Liao, Meng.,Zhao, Haoxing.,Liu, Longqian.,Li, Qian.,Dai, Yun.,...&Zhou, Yifeng.(2016).Training to improve contrast sensitivity in amblyopia: correction of high-order aberrations.SCIENTIFIC REPORTS,6.
MLA	Liao, Meng,et al."Training to improve contrast sensitivity in amblyopia: correction of high-order aberrations".SCIENTIFIC REPORTS 6(2016).