Evaluation and comparison of N-cycloalkylformylated chitosan bis(arylcarbamate)s as chiral selectors for enantioseparation

doi:10.1039/c7nj01611e

CORC > 青岛生物能源与过程研究所 > 中国科学院青岛生物能源与过程研究所 > 条件保障部公共实验室

	Evaluation and comparison of N-cycloalkylformylated chitosan bis(arylcarbamate)s as chiral selectors for enantioseparation
	Bai, Zheng-Wu 1; Yang, Fei 1; Fu, Ke-Qin 1; Wang, Xiao-Chen 1; Liu, Jian-De 1; Chen, Wei 1; Huang, Shao-Hua 2; Tang, Sheng 1
刊名	NEW JOURNAL OF CHEMISTRY
	2017-10-07
卷号	41 期号:19 页码:10561-10567
DOI	10.1039/c7nj01611e
文献子类	Article
英文摘要	In order to systematically investigate the structural dependence on the properties of N-cycloalkyl-formylated chitosan bis(arylcarbamate)s, 3,5-dimethylphenylcarbamates of N-cyclopropylformylated, N-cyclobutylformylated, N-cyclopentylformylated and N-cyclohexylformylated chitosans were prepared as chiral selectors in the present study. Since both the molecular weights of chitosan and the substituents at the 3- and 6-positions of the phenylcarbamates are identical, the influences of the substituent at the 2-position on the solvent tolerability and enantioseparation performance of the chiral selectors were specifically compared and discussed. It was found that the solvent tolerability and enantioseparation performances of the chiral selectors obviously differed with the variation of the substituent at the 2-position of the glucosamine skeleton. Although all the chiral selectors generally showed satisfactory tolerability in ethyl acetate and acetone, the chiral selector with a three-membered ring exhibited much more preferable tolerability against tetrahydrofuran than the others with a four-, five- or six-membered ring. Enantioseparation results revealed that most of the chiral selectors exhibited powerful chiral recognition and enantioseparation abilities, and the chiral selector with a five-membered ring exhibited the best enantioseparation performance. The corresponding coated-type chiral stationary phases prepared from these chitosan-based chiral selectors were able to be complementary with each other and applied as promising chiral separation materials for enantiomeric separations.
WOS关键词	PERFORMANCE LIQUID-CHROMATOGRAPHY ; STATIONARY PHASES ; SILICA-GEL ; POLYSACCHARIDE DERIVATIVES ; ENANTIOMERS ; SEPARATION ; CELLULOSE ; DISCRIMINATION ; AMYLOSE ; HPLC
WOS研究方向	Chemistry
语种	英语
WOS记录号	WOS:000411768600008
资助机构	National Natural Science Foundation of China(51373127) ; Hubei Provincial Department of Education(D20161505)
内容类型	期刊论文
源URL	[http://ir.qibebt.ac.cn/handle/337004/9600]
专题	青岛生物能源与过程研究所_条件保障部公共实验室
作者单位	1.Wuhan Inst Technol, Sch Chem & Environm Engn, Wuhan 430205, Hubei, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biobased Mat, Qingdao 266101, Peoples R China
推荐引用方式 GB/T 7714	Bai, Zheng-Wu,Yang, Fei,Fu, Ke-Qin,et al. Evaluation and comparison of N-cycloalkylformylated chitosan bis(arylcarbamate)s as chiral selectors for enantioseparation[J]. NEW JOURNAL OF CHEMISTRY,2017,41(19):10561-10567.
APA	Bai, Zheng-Wu.,Yang, Fei.,Fu, Ke-Qin.,Wang, Xiao-Chen.,Liu, Jian-De.,...&Tang, Sheng.(2017).Evaluation and comparison of N-cycloalkylformylated chitosan bis(arylcarbamate)s as chiral selectors for enantioseparation.NEW JOURNAL OF CHEMISTRY,41(19),10561-10567.
MLA	Bai, Zheng-Wu,et al."Evaluation and comparison of N-cycloalkylformylated chitosan bis(arylcarbamate)s as chiral selectors for enantioseparation".NEW JOURNAL OF CHEMISTRY 41.19(2017):10561-10567.