Reinforcement of thermoplastic chitosan hydrogel using chitin whiskers optimized with response surface methodology

doi:10.1016/j.carbpol.2018.01.083

	Reinforcement of thermoplastic chitosan hydrogel using chitin whiskers optimized with response surface methodology
	Sun, Guohui 1; Zhang, Xin 1; Bao, Zixian 1,2; Lang, Xuqian 1; Zhou, Zhongzheng 1; Li, Yang 1; Feng, Chao 1; Chen, Xiguang 1
刊名	CARBOHYDRATE POLYMERS
	2018-06-01
卷号	189 页码:280-288
关键词	Hydroxybutyl Chitosan Hydrogel Chitin Whisker Box-behnken Design Response Surface Methodology Mechanical Strength
ISSN号	0144-8617
DOI	10.1016/j.carbpol.2018.01.083
文献子类	Article
英文摘要	To strengthen the mechanical strength of thermo-sensitive hydroxybutyl chitosan (HBC) hydrogel, chitin whiskers were used as sticker to fabricate reinforced HBC (HBCW) hydrogel by using response surface methodology. Unlike the intrinsic network of HBC hydrogel, HBCW hydrogel showed a laminar shape with firm structure. The preparation condition was optimized by three-factor-three-level Box-Behnken design. The maximum mechanical strength (1011.11 Pa) was achieved at 50 degrees C, when the concentrations of HBC and chitin whiskers were 5.1 wt% and 2.0 wt%, respectively. The effects of temperature, pH value and NaCl concentration on mechanical strength of HBCW hydrogels were investigated via the oscillatory stress sweeps. The results showed that HBCW hydrogel could reach the maximum stiffness (similar to 1126 Pa) at 37 degrees C pH 12.0. Low pH and high salty ions could decrease the stability of hydrogel, while chitin whiskers could increase the stress tolerance and related ruptured strain of HBCW hydrogels.
WOS关键词	DOUBLE-NETWORK HYDROGELS ; HIGH MECHANICAL STRENGTH ; DRUG-DELIVERY-SYSTEM ; EMBOLIC AGENT ; FILMS ; COMPOSITES ; RELEASE ; MATRIX ; GELS ; CELL
WOS研究方向	Chemistry ; Polymer Science
语种	英语
出版者	ELSEVIER SCI LTD
WOS记录号	WOS:000428322000035
资助机构	National Natural Science Foundation of China(81671828) ; Applied Basic Research Plan of Qingdao(16-5-1-70-jch)
内容类型	期刊论文
源URL	[http://ir.qibebt.ac.cn/handle/337004/10779]
专题	中国科学院青岛生物能源与过程研究所
通讯作者	Feng, Chao; Chen, Xiguang
作者单位	1.Ocean Univ China, Coll Marine Life Sci, 5 Yushan Rd, Qingdao 266003, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China
推荐引用方式 GB/T 7714	Sun, Guohui,Zhang, Xin,Bao, Zixian,et al. Reinforcement of thermoplastic chitosan hydrogel using chitin whiskers optimized with response surface methodology[J]. CARBOHYDRATE POLYMERS,2018,189:280-288.
APA	Sun, Guohui.,Zhang, Xin.,Bao, Zixian.,Lang, Xuqian.,Zhou, Zhongzheng.,...&Chen, Xiguang.(2018).Reinforcement of thermoplastic chitosan hydrogel using chitin whiskers optimized with response surface methodology.CARBOHYDRATE POLYMERS,189,280-288.
MLA	Sun, Guohui,et al."Reinforcement of thermoplastic chitosan hydrogel using chitin whiskers optimized with response surface methodology".CARBOHYDRATE POLYMERS 189(2018):280-288.