Hyperpolarized Xe-129 Magnetic Resonance Imaging Sensor for H2S
Bouchard, Louis S.2; Liu, Maili1; Yang, Shengjun1; Deng, He1; Zhou, Xin1; Ren, Lili1; Jiang, Weiping1; Yuan, Yaping1
刊名CHEMISTRY-A EUROPEAN JOURNAL
2017-06-07
卷号23期号:32页码:7648-7652
关键词Cryptophane Hydrogen Sulfide Hyperpolarization Imaging Agents Xenon
DOI10.1002/chem.201605768
文献子类Article
英文摘要A new magnetic resonance imaging (MRI) molecular sensor for hydrogen sulfide detection and imaging using the nuclear spin resonance of hyperpolarized Xe-129 is developed. The designed MRI sensor employs cryptophane for NMR sensing, together with an azide group serving as a reaction site. It demonstrates a "proof-of-concept" that a fluorescent H2S probe can be linked to a xenon-binding cryptophane and thereby converted into an MRI probe, which could provide a very generalizable template.
WOS关键词HUMAN CARBONIC-ANHYDRASE ; HYDROGEN-SULFIDE ; FLUORESCENT-PROBES ; NMR-SPECTROSCOPY ; XENON NMR ; SIGNAL AMPLIFICATION ; BIOLOGICAL-SYSTEMS ; BIOSENSOR ; MRI ; DESIGN
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000402799200003
资助机构Natural Science Foundation of China(81227902 ; Natural Science Foundation of China(81227902 ; National Program for Support of Eminent Professionals (National Program for Support of Topnotch Young Professionals) ; National Program for Support of Eminent Professionals (National Program for Support of Topnotch Young Professionals) ; 81625011) ; 81625011) ; Natural Science Foundation of China(81227902 ; Natural Science Foundation of China(81227902 ; National Program for Support of Eminent Professionals (National Program for Support of Topnotch Young Professionals) ; National Program for Support of Eminent Professionals (National Program for Support of Topnotch Young Professionals) ; 81625011) ; 81625011)
内容类型期刊论文
源URL[http://ir.wipm.ac.cn/handle/112942/11491]  
专题武汉物理与数学研究所_磁共振基础研究部
作者单位1.Chinese Acad Sci, Natl Ctr Magnet Resonance Wuhan, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan Inst Phys & Math,Key Lab Magnet Resonance B, Wuhan 430071, Peoples R China
2.Univ Calif Los Angeles, Dept Chem & Biochem, Calif NanoSyst Inst, Mol Biol Inst, Los Angeles, CA 90095 USA
推荐引用方式
GB/T 7714
Bouchard, Louis S.,Liu, Maili,Yang, Shengjun,et al. Hyperpolarized Xe-129 Magnetic Resonance Imaging Sensor for H2S[J]. CHEMISTRY-A EUROPEAN JOURNAL,2017,23(32):7648-7652.
APA Bouchard, Louis S..,Liu, Maili.,Yang, Shengjun.,Deng, He.,Zhou, Xin.,...&Yuan, Yaping.(2017).Hyperpolarized Xe-129 Magnetic Resonance Imaging Sensor for H2S.CHEMISTRY-A EUROPEAN JOURNAL,23(32),7648-7652.
MLA Bouchard, Louis S.,et al."Hyperpolarized Xe-129 Magnetic Resonance Imaging Sensor for H2S".CHEMISTRY-A EUROPEAN JOURNAL 23.32(2017):7648-7652.
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