Variation in Phenolic Profile, beta-Carotene and Flavonoid Contents, Biological Activities of Two Tagetes Species from Pakistani Flora

doi:10.1002/cbdv.201600463

CORC > 武汉物理与数学研究所 > 中国科学院武汉物理与数学研究所 > 磁共振基础研究部

	Variation in Phenolic Profile, beta-Carotene and Flavonoid Contents, Biological Activities of Two Tagetes Species from Pakistani Flora
	Janneh, Omar 4; Hanif, Muhammad Asif 1; Hussain, Abdullah Ijaz 5; Ayub, Muhammad Adnan 1,5; Chatha, Shahzad Ali Shahid 5; Kamal, Ghulam Mustafa 2,5,6; Shahid, Muhammad 3
刊名	CHEMISTRY & BIODIVERSITY
	2017-06-01
卷号	14 期号:6
关键词	Dpph Radical Scavenging Phenolic Acids Flavonoids Caffeic Acid Tagetes Erecta
DOI	10.1002/cbdv.201600463
文献子类	Article
英文摘要	The objective of present study was to evaluate the variation in phenolic profile, beta-carotene, flavonoid contents, antioxidant and antimicrobial properties of Tagetes erecta and Tagetes patula (T. erecta and T. patula) through different in vitro assays. Antioxidant activity was determined through 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging and inhibition of linoleic acid peroxidation assays and antibacterial and antifungal activities studied using the disc diffusion and resazurin microtiter-plate assays against bacterial and fungal strains. Moreover, total phenolics (TP), total carotenoids (TC) and total flavonoids (TF) were also determined. Highest (TP 35.8 mg GAE/g) and TF (16.9 mg CE/g) contents were found in MeOH extract of T. patula. T. erecta extract showed higher TC contents (6.45 mg/g) than T. patula extract (6.32 mg/g). T. erecta exhibited the highest DPPH radical-scavenging activity (IC50) (5.73 mu g/mL) and inhibition of linoleic acid peroxidation (80.1%). RP-HPLC revealed the presence of caffeic acid, sinapic acid and ferulic acid in Tagetes extracts, m-coumaric acid in T. erecta whereas chlorogenic acid in T. patula extract only. Both extracts possessed promising antimicrobial activity compared to the ciprofloxacin and flumequine (+ve controls) against Bacillus subtilis and Alternaria alternate. Both extract were rich source of polyphenols exhibiting excellent biological activities.
WOS关键词	ANTIOXIDANT ACTIVITY ; ESSENTIAL OILS ; L. ; MARIGOLD ; ANTIBACTERIAL ; COMPONENTS ; EXTRACTS ; LYCOPENE ; LUTEIN ; CULTIVARS
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
WOS记录号	WOS:000405126900002
内容类型	期刊论文
源URL	[http://ir.wipm.ac.cn/handle/112942/11464]
专题	武汉物理与数学研究所_磁共振基础研究部
作者单位	1.Univ Agr Faisalabad, Dept Chem, Faisalabad, Pakistan 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Univ Agr Faisalabad, Dept Biochem, Faisalabad, Pakistan 4.St Georges Univ London, Inst Med & Biomed Educ, London SW17 0RE, England 5.Govt Coll Univ, Dept Chem, Nat Prod & Synthet Chem Lab, Faisalabad, Pakistan 6.Chinese Acad Sci, Key Lab Magnet Resonance Biol Syst, State Key Lab Magnet Resonance & Atom & Mol Phys, Ctr Magnet Resonance,Wuhan Inst Phys & Math, Wuhan 430071, Peoples R China
推荐引用方式 GB/T 7714	Janneh, Omar,Hanif, Muhammad Asif,Hussain, Abdullah Ijaz,et al. Variation in Phenolic Profile, beta-Carotene and Flavonoid Contents, Biological Activities of Two Tagetes Species from Pakistani Flora[J]. CHEMISTRY & BIODIVERSITY,2017,14(6).
APA	Janneh, Omar.,Hanif, Muhammad Asif.,Hussain, Abdullah Ijaz.,Ayub, Muhammad Adnan.,Chatha, Shahzad Ali Shahid.,...&Shahid, Muhammad.(2017).Variation in Phenolic Profile, beta-Carotene and Flavonoid Contents, Biological Activities of Two Tagetes Species from Pakistani Flora.CHEMISTRY & BIODIVERSITY,14(6).
MLA	Janneh, Omar,et al."Variation in Phenolic Profile, beta-Carotene and Flavonoid Contents, Biological Activities of Two Tagetes Species from Pakistani Flora".CHEMISTRY & BIODIVERSITY 14.6(2017).