Hemodynamics analysis of the serial stenotic coronary arteries.

	Hemodynamics analysis of the serial stenotic coronary arteries.
	Liu, Xin ; Peng, Changnong ; Xia, Yufa ; Gao, Zhifan ; Xu, Pengcheng ; Wang, Xiaoqing ; Xian, Zhanchao ; Yin, Youbing ; Jiao, Liqun ; Wang, Defeng
刊名	BIOMEDICAL ENGINEERING ONLINE
	2017
文献子类	期刊论文
英文摘要	Coronary arterial stenoses, particularly serial stenoses in a single branch, are responsible for complex hemodynamic properties of the coronary arterial trees, and the uncertain prognosis of invasive intervention. Critical information of the blood flow redistribution in the stenotic arterial segments is required for the adequate treatment planning. Therefore, in this study, an image based non-invasive functional assessment is performed to investigate the hemodynamic significances of serial stenoses. Twenty patient-specific coronary arterial trees with different combinations of stenoses were reconstructed from the computer tomography angiography for the evaluation of the hemodynamics. Our results showed that the computed FFR based on CTA images (FFRCT) pullback curves with wall shear stress (WSS) distribution could provide more effectively examine the physiological significance of thelocations of the segmental narrowing and the curvature of the coronary arterial segments. The paper thus provides the diagnostic efficacy of FFRCT pullback curve for noninvasive quantification of thehemodynamics of stenotic coronary arteries with serial lesions, compared to the gold standard invasive FFR, to provide a reliable physiological assessment of significant amount of coronary artery stenosis. Further, we were also able to demonstrate the potential of carrying out virtual revascularization, to enable more precise PCI procedures and improve their outcomes.
URL标识	查看原文
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/12627]
专题	深圳先进技术研究院_数字所
作者单位	BIOMEDICAL ENGINEERING ONLINE
推荐引用方式 GB/T 7714	Liu, Xin , Peng, Changnong , Xia, Yufa ,et al. Hemodynamics analysis of the serial stenotic coronary arteries.[J]. BIOMEDICAL ENGINEERING ONLINE,2017.
APA	Liu, Xin ., Peng, Changnong ., Xia, Yufa ., Gao, Zhifan ., Xu, Pengcheng .,...& Zhang, Heye.(2017).Hemodynamics analysis of the serial stenotic coronary arteries..BIOMEDICAL ENGINEERING ONLINE.
MLA	Liu, Xin ,et al."Hemodynamics analysis of the serial stenotic coronary arteries.".BIOMEDICAL ENGINEERING ONLINE (2017).