A Method for Systematically Evaluating the Hemostatic Ability of Hydrogels in vitro

	A Method for Systematically Evaluating the Hemostatic Ability of Hydrogels in vitro
	Jingwan Luo; Longxiang Lin; Nina Liao; Keke Zhang; Chang Liu; Yu-Long Sun
刊名	Bio-Medical Materials and Engineering
	2017
文献子类	期刊论文
英文摘要	The bursting strength is a key parameter to assess hemostatic ability of tissue sealants. It is associated to mechanical property of the materials as well as the binding strength of the materials to the tissues. It could be also associated to the testing conditions, such as temperature and wound size. Few works have been systematically investigated the relationship of the hemostatic ability of hydrogels with the above factors. This study introduced a method to systematically investigate the effect of the thickness, covered area, and components of hydrogels, the temperature, and the wound size on the bursting strength of hydrogels. The bursting strength of gelation hydrogel and fibrin glue were assessed with the system. This method could quantitatively investigate the effect of material properties and testing conditions on the bursting strength of material. It could also suggest us a minimum dosage of tissue sealant used in the both animal study and clinical practice. This study proved that the method we proposed is reliable to assess the bursting strength of materials with a potential hemostatic application.
URL标识	查看原文
语种	英语
WOS记录号	WOS:000416152400010
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/12153]
专题	深圳先进技术研究院_医工所
作者单位	Bio-Medical Materials and Engineering
推荐引用方式 GB/T 7714	Jingwan Luo,Longxiang Lin,Nina Liao,et al. A Method for Systematically Evaluating the Hemostatic Ability of Hydrogels in vitro[J]. Bio-Medical Materials and Engineering,2017.
APA	Jingwan Luo,Longxiang Lin,Nina Liao,Keke Zhang,Chang Liu,&Yu-Long Sun.(2017).A Method for Systematically Evaluating the Hemostatic Ability of Hydrogels in vitro.Bio-Medical Materials and Engineering.
MLA	Jingwan Luo,et al."A Method for Systematically Evaluating the Hemostatic Ability of Hydrogels in vitro".Bio-Medical Materials and Engineering (2017).