Preparation of Cu2+-Chitosan Quaternary Ammonium Salt-g-Poly(acrylicacid) with Efficient Antibacterial Activity

doi:10.7503/cjcu20160626

CORC > 上海应用物理研究所 > 中国科学院上海应用物理研究所 > 中科院上海应用物理研究所2011-2017年

	Preparation of Cu2+-Chitosan Quaternary Ammonium Salt-g-Poly(acrylicacid) with Efficient Antibacterial Activity
	Li, H; Xing, Z; Li, R; Zhang, MX; Wang, ML; Tan, YZ; Wu, GZ
刊名	CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
	2017
卷号	38 期号:5 页码:902-906
关键词	Schiff-bases Chitosan Complexes Substitution Binding Agent Dyes
ISSN号	0251-0790
DOI	10.7503/cjcu20160626
文献子类	期刊论文
英文摘要	Acrylic acid(AAc) was grafted to chitosan quaternary ammonium salt(HACC) by ammonium persulfate as an initiator. HACC-g-PAAc-Cu2+ with efficient antibacterial activity was further prepared through complexation of Cu2+ with HACC-g-PAAc. The chemical structure of the grafted HACC was characterized by Fourier transform infrared spectroscopy and proton nuclear magnetic resonance(H-1 NMR). The capacity of grafted HACC loading Cu2+ was determined by ultraviolet-visible spectroscopy(UV-Vis) and thermagravimetric analysis(TGA). Antimicrobial property of HACC-Cu2+ and HACC-g-PAAc-Cu2+ against staphylococcus aurous (S. Aurous) and E. coli bacillus were tested. Toxicity for oral intake of mice and coating irritation on rabbit skin of HACC-Cu2+ and HACC-g-PAAc-Cu2+ were also evaluated. The property of antibacterial and capacity of complexing Cu2+ can be improved by grafting of AAc. The molar ratio of Cu2+ / HACC increased from 3 : 7 be. fore grafting to 1 : 1 after grafting. The minimum inhibitory concentration(MIC) of S. Aurous and E. coli bacillus decreased from 60 mg/L to 9. 2 mg/L and 37 mg/L to 6. 3 mg/L. Moreover, HACC-Cu2+ and HACC-g-PAAc-Cu2+ have no toxic ingestion and skin irritation.
WOS关键词	SCHIFF-BASES ; CHITOSAN ; COMPLEXES ; SUBSTITUTION ; BINDING ; AGENT ; DYES
语种	英语
WOS记录号	WOS:000401966400029
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/28778]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
推荐引用方式 GB/T 7714	Li, H,Xing, Z,Li, R,et al. Preparation of Cu2+-Chitosan Quaternary Ammonium Salt-g-Poly(acrylicacid) with Efficient Antibacterial Activity[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2017,38(5):902-906.
APA	Li, H.,Xing, Z.,Li, R.,Zhang, MX.,Wang, ML.,...&Wu, GZ.(2017).Preparation of Cu2+-Chitosan Quaternary Ammonium Salt-g-Poly(acrylicacid) with Efficient Antibacterial Activity.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,38(5),902-906.
MLA	Li, H,et al."Preparation of Cu2+-Chitosan Quaternary Ammonium Salt-g-Poly(acrylicacid) with Efficient Antibacterial Activity".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 38.5(2017):902-906.