A new tetraphenylethylene based AIE probe for light-up and discriminatory detection of Cys over Hcy and GSH

	A new tetraphenylethylene based AIE probe for light-up and discriminatory detection of Cys over Hcy and GSH
	Jiang, Guoyu 1; Liu, Xiang 1; Chen, Qingqing 1; Zeng, Guanjie 1; Wu, Yongquan 1; Dong, Xiaobiao 2; Zhang, Guanxin 2; Li, Yongdong 1; Fan, Xiaolin 1; Wang, Jianguo 1
刊名	SENSORS AND ACTUATORS B-CHEMICAL
	2017-11-01
卷号	252 页码:712-716
关键词	Fluorescence Turn-on Sensor Aggregation Induced Emission Discriminatory Detection Of Cys Tetraphenylethylene Derivatives
英文摘要	A tetraphenylethylene based aggregation induced emission (AIE) probe, TPENNO2, bearing a 2,4-dinitrobenzenesulfonyl pendant was designed and synthesized for light-up and discriminatory detection of Cys over Hcy and GSH in PBS. The 2,4-dinitrobenzenesulfonyl group quenched the fluorescence of TPENNO2. While after thiol group promoted nucleophilic aromatic substitution reaction, TPENNO2 can be converted to fluorescent TPENH2. The discriminatory detection of Cys over Hcy and GSH comes from the different reaction kinetic profiles of TPENNO2 with the thiol residues of Cys, Hcy and GSH. Moreover, TPENNO2 can be used to image biothiols in living HeLa cells. (C) 2017 Elsevier B.V. All rights reserved.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/39332]
专题	化学研究所_有机固体实验室
作者单位	1.Gannan Normal Univ, Key Lab Organopharmaceut Chem, Ganzhou 341000, Peoples R China 2.Chinese Acad Sci, Inst Chem, Organ Solids Lab, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Jiang, Guoyu,Liu, Xiang,Chen, Qingqing,et al. A new tetraphenylethylene based AIE probe for light-up and discriminatory detection of Cys over Hcy and GSH[J]. SENSORS AND ACTUATORS B-CHEMICAL,2017,252:712-716.
APA	Jiang, Guoyu.,Liu, Xiang.,Chen, Qingqing.,Zeng, Guanjie.,Wu, Yongquan.,...&Wang, Jianguo.(2017).A new tetraphenylethylene based AIE probe for light-up and discriminatory detection of Cys over Hcy and GSH.SENSORS AND ACTUATORS B-CHEMICAL,252,712-716.
MLA	Jiang, Guoyu,et al."A new tetraphenylethylene based AIE probe for light-up and discriminatory detection of Cys over Hcy and GSH".SENSORS AND ACTUATORS B-CHEMICAL 252(2017):712-716.