Palhinine A, a Novel Alkaloid from Palhinhaea cernua

doi:10.1021/ol101602n

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	Palhinine A, a Novel Alkaloid from Palhinhaea cernua
	Zhao, Fu-Wei 1,2; Sun, Qian-Yun 3,4; Yang, Fu-Mei 3,4; Hu, Guang-Wan 1; Luo, Ji-Feng 1; Tang, Gui-Hua1,2 ; Wang, Yue-Hu1 ; Long, Chun-Lin 1,5
刊名	ORGANIC LETTERS
	2010-09-03
卷号	12 期号:17 页码:3922-3925
ISSN号	1523-7060
DOI	10.1021/ol101602n
通讯作者	wangyuehu@mail.kib.ac.cn ; long@mail.kib.ac.cn
文献子类	Article
英文摘要	Palhinine A, a novel C(16)N-type Lycopodium alkaloid with a unique 5/6/6/9 tetracyclic ring system, was isolated from the whole plant of Palhinhaea cernua L. (Lycopodiaceae). Its structure was elucidated by spectroscopic methods, and the absolute configuration was determined by single-crystal X-ray diffraction analysis using the Flack parameter. Palhinine A is reported as the first example of Lycopodium alkaloids of which C-16 is fused to a new ring through a C-16 C-4 lingkage.
学科主题	Chemistry, Organic
WOS关键词	ASYMMETRIC TOTAL SYNTHESES ; LYCOPODIUM ALKALOIDS ; INHIBITING ACETYLCHOLINESTERASE ; SERRATUM ; (+)-MAGELLANINONE ; (-)-MAGELLANINE ; HAMILTONII ; HUPERZINE ; AGENT ; ASSAY
WOS研究方向	Chemistry
语种	英语
WOS记录号	WOS:000281180700050
资助机构	This work was funded by the National Natural Science Foundation of China (No. 20972166), the National Basic Research Program of China (973 Program) (No. 2009CB526512), the Ministry of Education of China through its 111 and 985 Projects (B08044 and MUC 985), and the Knowledge Innovation Project of the Chinese Academy of Sciences. We appreciate Dr. Jia-Liang Zhong who works at the Shanghai Institute of Pharmaceutical Industry, who measured and elucidated the crystal structure, and Dr. Xiao-Nian Li at the Kunming Institute of Botany for his help in the experiment. We are also grateful to Adam Kavalier, who is a phytochemist at the Lehman College, the City University of New York, New York, for editing the English.
公开日期	2011-12-26
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/3206]
专题	昆明植物研究所_资源植物与生物技术所级重点实验室
作者单位	1.Chinese Acad Sci, Key Lab Econ Plants & Biotechnol, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Guiyang 550002, Peoples R China 4.Key Lab Chem Nat Prod, Guiyang, Guizhou Prov, Peoples R China 5.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Fu-Wei,Sun, Qian-Yun,Yang, Fu-Mei,et al. Palhinine A, a Novel Alkaloid from Palhinhaea cernua[J]. ORGANIC LETTERS,2010,12(17):3922-3925.
APA	Zhao, Fu-Wei.,Sun, Qian-Yun.,Yang, Fu-Mei.,Hu, Guang-Wan.,Luo, Ji-Feng.,...&Long, Chun-Lin.(2010).Palhinine A, a Novel Alkaloid from Palhinhaea cernua.ORGANIC LETTERS,12(17),3922-3925.
MLA	Zhao, Fu-Wei,et al."Palhinine A, a Novel Alkaloid from Palhinhaea cernua".ORGANIC LETTERS 12.17(2010):3922-3925.